Heliox

From Wikipedia, the free encyclopedia

See Heliox (cryogenic equipment) for another use of the word Heliox

Heliox is a breathing gas that is composed of a mixture of helium (He) and oxygen (O₂).

Heliox has been used in a medical context since the 1930s, and although the medical community adopted its use initially to alleviate the symptoms of upper airway obstruction, its range of medical uses has since expanded greatly, most of which are dependent on the low density of the gas.^[1] Heliox is also used in saturation diving and sometimes during the deep phase of technical dives.

[edit] Medical uses

In medicine, "heliox" generally describes a mixture that is 21% O₂ (the same as air) and 79% He, although other mixtures are available.

Airway resistance is dictated by the diameter of the airways and by the density of the inspired gas. Therefore when nitrogen (of air) is replaced by helium, airway resistance is reduced due to the lower density of the inspired gas. This means that when one breathes Heliox, airway resistance is less, and therefore the mechanical energy required to ventilate the lungs, or the Work of Breathing (WOB) is decreased. Heliox is used mainly in the alleviation of many medical conditions that involve a decrease in airway diameter (and consequently increased airway resistance), such as upper airway obstruction, asthma, chronic obstructive pulmonary disease (COPD), bronchiolitis and croup. Patients with these conditions may suffer a range of symptoms including dyspnea (breathlessness), hypoxemia (below-normal oxygen content in the arterial blood) and eventually a weakening of the respiratory muscles due to exhaustion, which can lead to respiratory failure and require intubation and mechanical ventilation - Heliox may reduce all these effects, making it easier for the patient to breathe, and as it will reduce work of breathing, Heliox can help to prevent this respiratory failure.^[2] Heliox has also found utility in the weaning of patients off mechanical ventilation, and in the nebulization of inhalable drugs, particularly for the elderly.^[3] Research has also indicated advantages in using helium/oxygen mixtures in delivery of anaesthesia.^[4]

[edit] Diving uses

Due to the expense of helium^[5], heliox is most likely to be used in deep commercial diving although it is sometimes used by diving enthusiasts using gas conserving rebreathers.

The proportion of oxygen in a diving mix depends on the maximum depth of the dive plan but is often hypoxic and typically 10%. Each mix is bespoke and is created using gas blending techniques which often involve the use of booster pumps to achieve typical diving cylinder pressures of 200 bar / 3000 psi from lower pressure banks of oxygen and helium cylinders.

Because sound travels faster in Heliox than in air, voice formants are raised, making divers' speech very high-pitched, and hard to understand to people not used to it.

Trimix is a close rival and slightly less expensive, deep diving, alternative to Heliox. Trimix is often used in commercial diving and in technical diving.

[edit] References

1. ^ BOC Medical (a trading name of BOC Limited). Heliox product information.
2. ^ BOC Medical. Heliox data sheet.
3. ^ Lee DL, Hsu CW, Lee H, Chang HW, Huang YC. Beneficial effects of albuterol therapy driven by heliox versus by oxygen in severe asthma exacerbation.
4. ^ Buczkowski, PW; Fombon, FN; Russell, WC and Thompson, PJ. Effects of helium on high frequency jet ventilation in model of airway stenosis.
5. ^ Example pricing for filling cylinders. Retrieved on 2008-01-10.

Please help improve this article or section by expanding it. Further information might be found on the talk page or at requests for expansion. (January 2008)