Halohydrin
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A halohydrin is a type of chemical compound or functional group in which one carbon atom has a substituent of the halogen group and an adjacent carbon atom has a hydroxyl substituent.
Halohydrin formation:
- from an alkene in a halohydrin formation reaction
- from an epoxide by a hydrohalic acid
Halohydrin reactions:
- In presence of a base, such as potassium hydroxide, a halohydrin may undergo internal SN2 reaction to form an epoxide. This is the reverse of the formation reaction from an epoxide.
- Epoxidation in biological systems can be catalyzed by halohydrin dehalogenase.
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