From Wikipedia, the free encyclopedia
Hairy RNA localisation element (HLE) |
|
Type: |
Cis-reg; |
2° structure: |
Published; PubMed |
Seed alignment: |
PubMed |
Avg length: |
130.5 nucleotides |
Avg identity: |
89% |
|
The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species.
[edit] References
- ^ Bullock, SL; Zicha D, Ish-Horowicz D (2003). "The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport". EMBO J 22: 2484–2494. doi:10.1093/emboj/cdg230. PMID 12743042.
[edit] External links