Hairy RNA localisation element (HLE)

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Hairy RNA localisation element (HLE)
Template:Abbreviation
Type: Cis-reg;
2° structure: Published; PubMed
Seed alignment: PubMed
Avg length: 130.5 nucleotides
Avg identity: 89%

The hairy localisation element (HLE) is an RNA element found in the 3' UTR of the hairy gene. HLE contains two stem-loops. HLE is essential for the mediation of apical localisation and the two stem-loop structures act to allow the recognition of hairy mRNA by the localisation machinery.[1] HLE is found in Drosophila species.

[edit] References

  1. ^ Bullock, SL; Zicha D, Ish-Horowicz D (2003). "The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport". EMBO J 22: 2484–2494. doi:10.1093/emboj/cdg230. PMID 12743042. 

[edit] External links