Guanylin
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guanylate cyclase activator 2A (guanylin)
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Identifiers | |
Symbol | GUCA2A |
Alt. Symbols | GUCA2 |
Entrez | 2980 |
HUGO | 4682 |
OMIM | 139392 |
RefSeq | NM_033553 |
UniProt | Q02747 |
Other data | |
Locus | Chr. 1 p35-p34 |
Guanylin is a 15 amino acid peptide that is secreted by goblet cells in the colon. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia.