Guanosine phosphorylase

From Wikipedia, the free encyclopedia

In enzymology, a guanosine phosphorylase (EC 2.4.2.15) is an enzyme that catalyzes the chemical reaction

guanosine + phosphate guanine + alpha-D-ribose 1-phosphate

Thus, the two substrates of this enzyme are guanosine and phosphate, whereas its two products are guanine and alpha-D-ribose 1-phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is guanosine:phosphate alpha-D-ribosyltransferase. This enzyme participates in purine metabolism.

[edit] References

• IUBMB entry for 2.4.2.15
• BRENDA references for 2.4.2.15 (Recommended.)
• PubMed references for 2.4.2.15
• PubMed Central references for 2.4.2.15
• Google Scholar references for 2.4.2.15
• Yamada EW (1961). "The phosphorolysis of nucleosides by rabbit bone marrow". J. Biol. Chem. 236: 3043–3046. 

[edit] External links

The CAS registry number for this enzyme class is 9030-28-8.

• IUBMB entry for 2.4.2.15

• KEGG entry for 2.4.2.15

• BRENDA entry for 2.4.2.15

• NiceZyme view of 2.4.2.15

• EC2PDB: PDB structures for 2.4.2.15

• PRIAM entry for 2.4.2.15

• PUMA2 entry for 2.4.2.15

• IntEnz: Integrated Enzyme entry for 2.4.2.15

• MetaCyc entry for 2.4.2.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047975: guanosine phosphorylase

• AMIGO entry for GO code 0047975: guanosine phosphorylase