Guanidinoacetate kinase

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In enzymology, a guanidinoacetate kinase (EC 2.7.3.1) is an enzyme that catalyzes the chemical reaction

ATP + guanidinoacetate $\rightleftharpoons$ ADP + phosphoguanidinoacetate

Thus, the two substrates of this enzyme are ATP and guanidinoacetate, whereas its two products are ADP and phosphoguanidinoacetate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP:guanidinoacetate N-phosphotransferase. This enzyme is also called glycocyamine kinase. This enzyme participates in arginine and proline metabolism.

[edit] References

IUBMB entry for 2.7.3.1
BRENDA references for 2.7.3.1 (Recommended.)
PubMed references for 2.7.3.1
PubMed Central references for 2.7.3.1
Google Scholar references for 2.7.3.1
HOBSON GE, REES KR (1957). "The annelid phosphokinases". Biochem. J. 65: 305–7. PMID 13403909.
Pradel LA, Kassab R, Conlay C, Nguyen Van Thoai (1968). "[Properties and amino acid composition of purified ATP: guanidinoacetate phosphotransferase]". Biochim. Biophys. Acta. 154: 305–14. PMID 5637051.
Pradel L-A, Kassab R and Thoai NV (1964). "Sur l'acide adenosine-triphosphorique:guanidoacetate phosphotransferase". Biochim. Biophys. Acta 81: 86–95.
Thoai NV (1957). "Sur la taurocyamine et la glycocyamine phosphokinase". Bull. Soc. Chim. Biol. 39: 197–208.