GTPBP3

From Wikipedia, the free encyclopedia

GTP binding protein 3 (mitochondrial)

Identifiers

GTPBP3; MSS1; FLJ14700; GTPBG3; MTGP1; THDF1

External IDs

OMIM: 608536 MGI: 1917609 HomoloGene: 6600

Gene ontology
Molecular Function:	• nucleotide binding • GTPase activity • GTP binding
Cellular Component:	• intracellular
Biological Process:	• tRNA modification

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_032620 (mRNA)
NP_116009 (protein)

NM_032544 (mRNA)
NP_115933 (protein)

Location

Chr 19: 17.31 - 17.31 Mb

Chr 8: 74.42 - 74.43 Mb

Pubmed search

[1]

[2]

GTP binding protein 3 (mitochondrial), also known as GTPBP3, is a human gene.^[1]

[edit] References

^ Entrez Gene: GTPBP3 GTP binding protein 3 (mitochondrial).

[edit] Further reading

Magrini SM, Papi MG, Marletta F, et al. (1993). "Chordoma-natural history, treatment and prognosis. The Florence Radiotherapy Department experience (1956-1990) and a critical review of the literature.". Acta oncologica (Stockholm, Sweden) 31 (8): 847-51. PMID 1290633.
Li X, Guan MX (2002). "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation.". Mol. Cell. Biol. 22 (21): 7701-11. PMID 12370316.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Li X, Guan MX (2004). "Identification and characterization of mouse GTPBP3 gene encoding a mitochondrial GTP-binding protein involved in tRNA modification.". Biochem. Biophys. Res. Commun. 312 (3): 747-54. doi:10.1016/j.bbrc.2003.10.187. PMID 14680828.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Bykhovskaya Y, Mengesha E, Wang D, et al. (2005). "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3.". Mol. Genet. Metab. 83 (3): 199-206. doi:10.1016/j.ymgme.2004.07.009. PMID 15542390.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801-14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.