GTF3C4

From Wikipedia, the free encyclopedia

General transcription factor IIIC, polypeptide 4, 90kDa

Identifiers

GTF3C4; FLJ21002; MGC138450; TFIII90; TFIIIC90; TFIIICdelta; TFiiiC2-90

External IDs

OMIM: 604892 MGI: 2138937 HomoloGene: 8147

Gene ontology
Molecular Function:	• DNA binding • RNA polymerase III transcription factor activity • H3/H4 histone acetyltransferase activity • enzyme activator activity • acyltransferase activity • transferase activity
Cellular Component:	• transcription factor TFIIIC complex • nucleus
Biological Process:	• transcription • transcription initiation from RNA polymerase III promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_012204 (mRNA)
NP_036336 (protein)

NM_172977 (mRNA)
NP_766565 (protein)

Location

Chr 9: 134.54 - 134.56 Mb

Chr 2: 28.65 - 28.66 Mb

Pubmed search

[1]

[2]

General transcription factor IIIC, polypeptide 4, 90kDa, also known as GTF3C4, is a human gene.^[1]

[edit] References

^ Entrez Gene: GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa.

[edit] Further reading

Dumay-Odelot H, Marck C, Durrieu-Gaillard S, et al. (2007). "Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC.". J. Biol. Chem. 282 (23): 17179-89. doi:10.1074/jbc.M611542200. PMID 17409385.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hsieh YJ, Kundu TK, Wang Z, et al. (1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity.". Mol. Cell. Biol. 19 (11): 7697-704. PMID 10523658.
Hsieh YJ, Wang Z, Kovelman R, Roeder RG (1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III.". Mol. Cell. Biol. 19 (7): 4944-52. PMID 10373544.
Jang KL, Collins MK, Latchman DS (1992). "The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC.". J. Acquir. Immune Defic. Syndr. 5 (11): 1142-7. PMID 1403646.