GRID1

From Wikipedia, the free encyclopedia

Glutamate receptor, ionotropic, delta 1

Identifiers

GRID1; KIAA1220

External IDs

OMIM: 610659 MGI: 95812 HomoloGene: 69017

Gene ontology
Molecular Function:	• receptor activity • ionotropic glutamate receptor activity • transporter activity • ion channel activity • extracellular-glutamate-gated ion channel activity • protein binding
Cellular Component:	• membrane • integral to membrane • outer membrane-bounded periplasmic space • postsynaptic membrane
Biological Process:	• ion transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_017551 (mRNA)
NP_060021 (protein)

NM_008166 (mRNA)
NP_032192 (protein)

Location

Chr 10: 87.35 - 88.12 Mb

Chr 14: 33.65 - 34.41 Mb

Pubmed search

[1]

[2]

Glutamate receptor, ionotropic, delta 1, also known as GRID1, is a human gene.^[1]

[edit] References

^ Entrez Gene: GRID1 glutamate receptor, ionotropic, delta 1.

[edit] Further reading

Guo SZ, Huang K, Shi YY, et al. (2007). "A case-control association study between the GRID1 gene and schizophrenia in the Chinese Northern Han population.". Schizophr. Res. 93 (1-3): 385-90. doi:10.1016/j.schres.2007.03.007. PMID 17490860.
Fallin MD, Lasseter VK, Avramopoulos D, et al. (2006). "Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios.". Am. J. Hum. Genet. 77 (6): 918-36. doi:10.1086/497703. PMID 16380905.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Yue Z, Horton A, Bravin M, et al. (2002). "A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice.". Neuron 35 (5): 921-33. PMID 12372286.
Ly CD, Roche KW, Lee HK, Wenthold RJ (2002). "Identification of rat EMAP, a delta-glutamate receptor binding protein.". Biochem. Biophys. Res. Commun. 291 (1): 85-90. doi:10.1006/bbrc.2002.6413. PMID 11829466.
Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (5): 337-45. PMID 10574462.
Roche KW, Ly CD, Petralia RS, et al. (1999). "Postsynaptic density-93 interacts with the delta2 glutamate receptor subunit at parallel fiber synapses.". J. Neurosci. 19 (10): 3926-34. PMID 10234023.
Treadaway J, Zuo J (1999). "Mapping of the mouse glutamate receptor delta1 subunit (Grid1) to chromosome 14.". Genomics 54 (2): 359-60. doi:10.1006/geno.1998.5599. PMID 9828146.
Yamazaki M, Araki K, Shibata A, Mishina M (1992). "Molecular cloning of a cDNA encoding a novel member of the mouse glutamate receptor channel family.". Biochem. Biophys. Res. Commun. 183 (2): 886-92. PMID 1372507.