Grape
From Wikipedia, the free encyclopedia
Grapes, red or green Nutritional value per 100 g (3.5 oz) |
||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Energy 70 kcal 290 kJ | ||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||
Percentages are relative to US recommendations for adults. Source: USDA Nutrient database |
A grape is the non-climacteric fruit that grows on the perennial and deciduous woody vines of the genus Vitis. Grapes can be eaten raw or used for making jam, juice, jelly, vinegar, wine, grape seed extracts and grape seed oil.
Contents |
[edit] Description
Grapes grow in clusters of 6 to 300, and can be crimson, black, dark blue, yellow, green and pink. However, "white" grapes are actually green in color, and are evolutionarily derived from the red grape. Mutations in two regulatory genes of white grapes turn off production of anthocyanins which are responsible for the color of red grapes.[1] Anthocyanins and other pigment chemicals of the larger family of polyphenols in red grapes are responsible for the varying shades of purple in red wines.[2][3]
[edit] Grapevines
Most grapes come from cultivars of Vitis vinifera, the European grapevine native to the Mediterranean and Central Asia. Minor amounts of fruit and wine come from American and Asian species such as:
- Vitis labrusca, the North American table and grape juice grapevines (including the concord cultivar), sometimes used for wine. Native to the Eastern United States and Canada.
- Vitis riparia, a wild vine of North America, sometimes used for winemaking and for jam. Native to the entire Eastern U.S. and north to Quebec.
- Vitis rotundifolia, the muscadines, used for jams and wine. Native to the Southeastern United States from Delaware to the Gulf of Mexico.
- Vitis vulpina Frost grape. Native to the United States Midwest east to the coast up through New York.
- Vitis amurensis Most important Asian species.
The sea grape Coccoloba uvifera is actually a member of the Buckwheat family Polygonaceae and is native to the islands of the Caribbean Sea.
[edit] Distribution and production
According to the Food and Agriculture Organization (FAO), 75,866 square kilometres of the world are dedicated to grapes. Approximately 71% of world grape production is used for wine, 27% as fresh fruit, and 2% as dried fruit. A portion of grape production goes to producing grape juice to be reconstituted for fruits canned "with no added sugar" and "100% natural". The area dedicated to vineyards is increasing by about 2% per year.
The following table of top wine-producers shows the corresponding areas dedicated to grapes for wine making:
Country | Area Dedicated |
---|---|
Spain | 11,750 km² |
France | 8,640 km² |
Italy | 8,270 km² |
Turkey | 8,120 km² |
United States | 4,150 km² |
Iran | 2,860 km² |
Romania | 2,480 km² |
Portugal | 2,160 km² |
Argentina | 2,080 km² |
Australia | 1,642 km² |
[edit] Seedless grapes
Seedlessness is a highly desirable subjective quality in table grape selection, and seedless cultivars now make up the overwhelming majority of table grape plantings. Because grapevines are vegetatively propagated by cuttings, the lack of seeds does not present a problem for reproduction. It is, however, an issue for breeders, who must either use a seeded variety as the female parent or rescue embryos early in development using tissue culture techniques.
There are several sources of the seedlessness trait, and essentially all commercial cultivators get it from one of three sources: Thompson Seedless, Russian Seedless, and Black Monukka, all being cultivars of Vitis vinifera. Numerous seedless cultivars, such as Einset Seedless, Reliance and Venus, have been specifically cultivated for hardiness and quality in the relatively cold climates of north-eastern United States and southern Ontario.[5]
Contrary to the improved eating quality of seedlessness is the loss of potential health benefits provided by the enriched phytochemical content of grape seeds (see Health claims).[6][7]
[edit] Raisins, currants, and sultanas
- See also: Dried vine fruit
In most of Europe, dried grapes are universally referred to as 'raisins' or the local equivalent. In the UK, three different varieties are recognised, forcing the EU to use the term "Dried vine fruit" in official documents.
A raisin is any dried grape. While raisin is a French loanword, the word in French refers to the fresh fruit; grappe (whence the English grape is derived) refers to the bunch (as in une grappe de raisins).
A currant is a dried Zante grape, the name being a corruption of the French raisin de Corinthe (Corinth grape). Note also that currant has come to refer also to the blackcurrant and redcurrant, two berries completely unrelated to grapes.
A sultana was originally a raisin made from a specific type of grape of Turkish origin, but the word is now applied to raisins made from common grapes and chemically treated to resemble the traditional sultana.
[edit] Health claims
[edit] French Paradox
Comparing diets among western countries, researchers have discovered that although the French tend to eat higher levels of animal fat, surprisingly the incidence of heart disease remains low in France, a phenomenon named the French Paradox thought to occur from protective benefits of regularly consuming red wine. Apart from potential benefits of alcohol itself, including reduced platelet aggregation and vasodilation[8], polyphenols (e.g., resveratrol) mainly in the grape skin provide other suspected health benefits, such as:[9]
- alteration of molecular mechanisms in blood vessels, reducing susceptibility to vascular damage
- decreased activity of angiotensin, a systemic hormone causing blood vessel constriction that would elevate blood pressure
- increased production of the vasodilator hormone, nitric oxide (endothelium-derived relaxing factor)
Although adoption of wine consumption is not recommended by some health authorities,[10] a significant volume of research indicates moderate consumption, such as one glass of red wine a day for women and two for men, may confer health benefits.[11][12][13] Emerging evidence is that wine polyphenols like resveratrol[14] provide physiological benefit whereas alcohol itself may have protective effects on the cardiovascular system.[15][16]
[edit] Resveratrol
Grape phytochemicals such as resveratrol, a polyphenol antioxidant, have been positively linked to inhibiting cancer, heart disease, degenerative nerve disease, viral infections and mechanisms of Alzheimer's disease.[17][18]
Protection of the genome through antioxidant actions may be a general function of resveratrol.[19] In laboratory studies, resveratrol bears a significant transcriptional overlap with the beneficial effects of calorie restriction in heart, skeletal muscle and brain. Both dietary interventions inhibit gene expression associated with heart and skeletal muscle aging, and prevent age-related heart failure.[20]
Resveratrol is the subject of several human clinical trials,[21] among which the most advanced is a one year dietary regimen in a Phase III study of elderly patients with Alzheimer's disease.[22]
Synthesized by many plants, resveratrol apparently serves antifungal and other defensive properties. Dietary resveratrol has been shown to modulate the metabolism of lipids and to inhibit oxidation of low-density lipoproteins and aggregation of platelets.[23]
Resveratrol is found in wide amounts among grape varieties, primarily in their skins and seeds which, in muscadine grapes, have about one hundred times higher concentration than pulp.[24] Fresh grape skin contains about 50 to 100 micrograms of resveratrol per gram.[25]
[edit] Anthocyanins and other phenolics
Anthocyanins tend to be the main polyphenolics in red grapes whereas flavan-3-ols (e.g., catechins) are the more abundant phenolic in white varieties.[26] Total phenolic content, an index of dietary antioxidant strength, is higher in red varieties due almost entirely to anthocyanin density in red grape skin compared to absence of anthocyanins in white grape skin.[26] It is these anthocyanins that are attracting the efforts of scientists to define their properties for human health.[27] Phenolic content of grape skin varies with cultivar, soil composition, climate, geographic origin, and cultivation practices or exposure to diseases, such as fungal infections.
Red wine offers health benefits more so than white because many beneficial compounds are present in grape skin, and only red wine is fermented with skins. The amount of fermentation time a wine spends in contact with grape skins is an important determinant of its resveratrol content.[20] Ordinary non-muscadine red wine contains between 0.2 and 5.8 mg/L [28], depending on the grape variety, because it is fermented with the skins, allowing the wine to absorb the resveratrol. By contrast, a white wine contains lower phenolic contents because it is fermented after removal of skins.
Wines produced from muscadine grapes may contain more than 40 mg/L, an exceptional phenolic content.[29][24] In muscadine skins, ellagic acid, myricetin, quercetin, kaempferol, and trans-resveratrol are major phenolics.[30] Contrary to previous results, ellagic acid and not resveratrol is the major phenolic in muscadine grapes.
[edit] Seed constituents
Since the 1980s, biochemical and medical studies have demonstrated significant antioxidant properties of grape seed oligomeric proanthocyanidins[31]. Together with tannins, polyphenols and polyunsaturated fatty acids, these seed constituents display inhibitory activities against several experimental disease models, including cancer, heart failure and other disorders of oxidative stress.[32][33]
Grape seed oil from crushed seeds is used in cosmeceuticals and skincare products for many perceived health benefits. Grape seed oil is notable for its high contents of tocopherols (vitamin E), phytosterols, and polyunsaturated fatty acids such as linoleic acid, oleic acid and alpha-linolenic acid.[34][35][36]
[edit] Concord grape juice
Commercial juice products from Concord grapes have been applied in medical research studies, showing potential benefits against the onset stage of cancer[37], platelet aggregation and other risk factors of atherosclerosis[38], loss of physical performance and mental acuity during aging[39] and hypertension in humans[40]. Interpretation of these results has implicated the exceptional content of Concord grape anthocyanins -- as many as 31 different pigment chemicals in this one species[41] -- for contributing to these and other potential benefits of having Concord grape products in the diet[42].
[edit] See also
[edit] Sources
- Footnotes
- ^ Walker AR, Lee E, Bogs J, McDavid DA, Thomas MR, Robinson SP (2007). "White grapes arose through the mutation of two similar and adjacent regulatory genes". Plant J 49 (5): 772–85. doi: . PMID 17316172.
- ^ Waterhouse AL. Wine phenolics. Ann N Y Acad Sci. 2002 May;957:21-36.[1]
- ^ Brouillard R, Chassaing S, Fougerousse A. Why are grape/fresh wine anthocyanins so simple and why is it that red wine color lasts so long? Phytochemistry. 2003 Dec;64(7):1179-86.[2]
- ^ Pernesz, G.. New Resistant Table Grape Cultivars Bred in Hungary. International Society for Horticultural Science.
- ^ Reisch BI, Peterson DV, Martens M-H. Table Grape Varieties for Cool Climates, Information Bulletin 234, Cornell University, New York State Agricultural Experiment Station[3]
- ^ Shi J, Yu J, Pohorly JE, Kakuda Y. (2003 Winter). "Polyphenolics in grape seeds-biochemistry and functionality.". . J Med Food. 2003 Winter;6(4):291-9. Retrieved on 2007-08-16.
- ^ Parry J, Su L, Moore J, Cheng Z, Luther M, Rao JN, Wang JY, Yu LL. (2006-05-31). "Chemical compositions, antioxidant capacities, and antiproliferative activities of selected fruit seed flours.". . J Agric Food Chem. 2006 May 31;54(11):3773-8. Retrieved on 2007-08-16.
- ^ Providência R. (2006). Cardiovascular protection from alcoholic drinks: scientific basis of the French Paradox. Rev Port Cardiol. 2006 Nov;25(11):1043-58. Abstract.
- ^ Opie LH, Lecour S. (2007). The red wine hypothesis: from concepts to protective signalling molecules. Eur Heart J. 2007 Jul;28(14):1683-93. Abstract.
- ^ American Heart Association, Alcohol, wine and cardiovascular disease.[4]
- ^ Alcohol. Harvard School of Public Health
- ^ Mukamal KJ, Kennedy M, Cushman M, Kuller LH, Newman AB, Polak J, Criqui MH, Siscovick DS. Alcohol consumption and lower extremity arterial disease among older adults: the cardiovascular health study. Am J Epidemiol. 2008 Jan 1;167(1):34-41.Abstract
- ^ de Lange DW, van de Wiel A. Drink to prevent: review on the cardioprotective mechanisms of alcohol and red wine polyphenols. Semin Vasc Med. 2004 May;4(2):173-86.Abstract
- ^ Das S, Das DK. Resveratrol: a therapeutic promise for cardiovascular diseases. Recent Patents Cardiovasc Drug Discov. 2007 Jun;2(2):133-8.Abstract
- ^ Sato M, Maulik N, Das DK. Cardioprotection with alcohol: role of both alcohol and polyphenolic antioxidants. Ann N Y Acad Sci. 2002 May;957:122-35. Abstract
- ^ Wollin SD, Jones PJ. Alcohol, red wine and cardiovascular disease. J Nutr. 2001 May;131(5):1401-4.Abstract
- ^ Shankar S, Singh G, Srivastava RK. Chemoprevention by resveratrol: molecular mechanisms and therapeutic potential. Front Biosci. 2007 Sep 1;12:4839-54.Abstract
- ^ Mancuso C, Bates TE, Butterfield DA, Calafato S, Cornelius C, De Lorenzo A, Dinkova Kostova AT, Calabrese V. Natural antioxidants in Alzheimer's disease. Expert Opin Investig Drugs. 2007 Dec;16(12):1921-31.Abstract
- ^ Gatz SA, Wiesmüller L. Take a break--resveratrol in action on DNA. Carcinogenesis. 2008 Feb;29(2):321-32.Abstract
- ^ Barger JL, Kayo T, Vann JM, Arias EB, Wang J, et al. (2008) A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice. PLoS ONE 3(6): e2264. doi:10.1371/journal.pone.0002264[5]
- ^ Listing of resveratrol clinical trials, ClinicalTrials.gov, a service of the US National Institutes of Health[6]
- ^ Randomized Trial of a Nutritional Supplement in Alzheimer's Disease, US Department of Veterans Affairs, Mount Sinai School of Medicine, May 2008 [7]
- ^ Chan, W. K., & Delucchi, A. B. (2000). Resveratrol, a red wine constituent, is a mechanism-based inactivator of cytochrome P450 3A4. Life Sci 67 (25): 3103-3112. Abstract.
- ^ a b LeBlanc, MR (2005). Cultivar, Juice Extraction, Ultra Violet Irradiation and Storage Influence the Stilbene Content of Muscadine Grapes (Vitis Rotundifolia Michx.). PhD Dissertation, Louisiana State University[8]
- ^ Li X, Wu B, Wang L, Li S. (2006). Extractable amounts of trans-resveratrol in seed and berry skin in Vitis evaluated at the germplasm level. J Agric Food Chem. 2006 Nov 15;54(23):8804-11. Abstract.
- ^ a b Cantos E, Espín JC, Tomás-Barberán FA. (2002). Varietal differences among the polyphenol profiles of seven table grape cultivars studied by LC-DAD-MS-MS. J Agric Food Chem. 2002 Sep 25;50(20):5691-6. Abstract.
- ^ Gross PM (2007). Scientists zero in on health benefits of berry pigments. Natural Products Information Center 2007 Jul 9. [9]
- ^ Gu X, Creasy L, Kester A, et al., Capillary electrophoretic determination of resveratrol in wines. J Agric Food Chem 47:3323-3277, 1999
- ^ Ector BJ, Magee JB, Hegwood CP, Coign MJ. Resveratrol Concentration in Muscadine Berries, Juice, Pomace, Purees, Seeds, and Wines. [10]
- ^ Pastrana-Bonilla E, Akoh CC, Sellappan S, Krewer G. (2003). Phenolic content and antioxidant capacity of muscadine grapes. J Agric Food Chem. 2003 Aug 27;51(18):5497-503 Abstract.
- ^ Bagchi D, Bagchi M, Stohs SJ, Das DK, Ray SD, Kuszynski CA, Joshi SS, Pruess HG. (2000-08-07). "Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention.". . Toxicology. 2000 Aug 7;148(2-3):187-97. Retrieved on 2007-08-16.
- ^ Agarwal C, Singh RP, Agarwal R. (2002-11-23). "Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release.". . Carcinogenesis. 2002 Nov;23(11):1869-76. Retrieved on 2007-08-16.
- ^ Bagchi D, Sen CK, Ray SD, Das DK, Bagchi M, Preuss HG, Vinson JA. (2003-02-01). "Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract.". . Mutat Res. 2003 Feb-Mar;523-524:87-97. Retrieved on 2007-08-16.
- ^ Beveridge TH, Girard B, Kopp T, Drover JC. Yield and composition of grape seed oils extracted by supercritical carbon dioxide and petroleum ether: varietal effects. J Agric Food Chem. 2005 Mar 9;53(5):1799-804. [11]
- ^ Crews C, Hough P, Godward J, Brereton P, Lees M, Guiet S, Winkelmann W. Quantitation of the main constituents of some authentic grape-seed oils of different origin. J Agric Food Chem. 2006 Aug 23;54(17):6261-5. [12]
- ^ Tangolar SG, Ozoğul Y, Tangolar S, Torun A. Evaluation of fatty acid profiles and mineral content of grape seed oil of some grape genotypes. Int J Food Sci Nutr. 2007 Sep 19;:1-8 [13]
- ^ Jung KJ, Wallig MA, Singletary KW. Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Lett. 2006 Feb 28;233(2):279-88. [14]
- ^ Shanmuganayagam D, Warner TF, Krueger CG, Reed JD, Folts JD. Concord grape juice attenuates platelet aggregation, serum cholesterol and development of atheroma in hypercholesterolemic rabbits. Atherosclerosis. 2007 Jan;190(1):135-42. [15]
- ^ Shukitt-Hale B, Carey A, Simon L, Mark DA, Joseph JA. Effects of Concord grape juice on cognitive and motor deficits in aging. Nutrition. 2006 Mar;22(3):295-302. [16]
- ^ Park YK, Kim JS, Kang MH. Concord grape juice supplementation reduces blood pressure in Korean hypertensive men: double-blind, placebo controlled intervention trial. Biofactors. 2004;22(1-4):145-7. [17]
- ^ Wu X, Prior RL. Systematic identification and characterization of anthocyanins by HPLC-ESI-MS/MS in common foods in the United States: fruits and berries. J Agric Food Chem. 2005 Apr 6;53(7):2589-99. [18]
- ^ The Berry Doctor. Berry king. The Berry Doctor's Journal, February 26, 2008 [19]
[edit] External links
- Taxonomic listings for Vitis genus, US Department of Agriculture, Germplasm Resources Information Network
- Wild Grapes
- Major wine varieties
- SAFECROP - Proceedings of the 5th International Workshop on Grapevine Downy and Powdery Mildew
- World's Healthiest Foods, in-depth nutrient profile for grapes
- Information on virus diseases of wine grapes