Grand challenges in global health
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The Grand Challenges in Global Health initiative is a partnership dedicated to supporting scientific and technical research to solve critical health problems in the developing world. Currently 14 independent "Grand Challenges" are supported. The initiative's partners are the Bill & Melinda Gates Foundation, the Canadian Institutes of Health Research, the Foundation for the National Institutes of Health [1], and the Wellcome Trust.
[edit] The Grand Challenges
Grand Challenge #1: Create Effective Single-Dose Vaccines that Can be used Soon After Birth
Grand Challenge #2: Prepare Vaccines that Do Not Require Refrigeration
Grand Challenge #3: Develop Needle-Free Delivery Systems for Vaccines
Grand Challenge #4: Devise Reliable Tests in Model Systems to Evaluate Live-attenuated Vaccines
Grand Challenge #5: Solve How to Design Antigens for Effective, Protective Immunity
Grand Challenge #6: Learn Which Immunological Responses Provide Protective Immunity
Grand Challenge #7: Develop a Genetic Strategy to Deplete or Incapacitate a Disease-transmitting Insect Population
Grand Challenge #8: Develop a Chemical Strategy to Deplete or Incapacitate a Disease-transmitting Insect Population
Grand Challenge #9: Create a Full Range of Optimal, Bioavailable Nutrients in a Single Staple Plant Species
Grand Challenge #10: Discover Drugs and Delivery Systems that Minimize the Likelihood of Drug Resistant Micro-organisms
Grand Challenge #11: Create Therapies that Can Cure Latent Infection
Grand Challenge #12: Create Immunological Methods that Can Cure Latent Infection
Grand Challenge #13: Develop Technologies that Permit Quantitative Assessment of Population Health
Grand Challenge #14: Develop Technologies that Allow Assessment of Individuals for Multiple Conditions or Pathogens at Point of Care