GPR34
From Wikipedia, the free encyclopedia
G protein-coupled receptor 34
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Identifiers | ||||||||||||||
Symbol(s) | GPR34; | |||||||||||||
External IDs | OMIM: 300241 MGI: 1346334 HomoloGene: 36174 | |||||||||||||
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Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 2857 | 23890 | ||||||||||||
Ensembl | ENSG00000171659 | ENSMUSG00000040229 | ||||||||||||
Uniprot | Q9UPC5 | Q3USC5 | ||||||||||||
Refseq | NM_001033513 (mRNA) NP_001028685 (protein) |
NM_011823 (mRNA) NP_035953 (protein) |
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Location | Chr X: 41.43 - 41.44 Mb | Chr X: 12.79 - 12.8 Mb | ||||||||||||
Pubmed search | [1] | [2] |
G protein-coupled receptor 34, also known as GPR34, is a human gene.[1]
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.[supplied by OMIM][1]
[edit] References
[edit] Further reading
- Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807–28. PMID 8889549.
- Marchese A, Sawzdargo M, Nguyen T, et al. (1999). "Discovery of three novel orphan G-protein-coupled receptors.". Genomics 56 (1): 12–21. doi: . PMID 10036181.
- Schöneberg T, Schulz A, Grosse R, et al. (1999). "A novel subgroup of class I G-protein-coupled receptors.". Biochim. Biophys. Acta 1446 (1-2): 57–70. PMID 10395919.
- Jacobi FK, Broghammer M, Pesch K, et al. (2000). "Physical mapping and exclusion of GPR34 as the causative gene for congenital stationary night blindness type 1.". Hum. Genet. 107 (1): 89–91. PMID 10982042.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi: . PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi: . PMID 16303743.
- Engemaier E, Römpler H, Schöneberg T, Schulz A (2006). "Genomic and supragenomic structure of the nucleotide-like G-protein-coupled receptor GPR34.". Genomics 87 (2): 254–64. doi: . PMID 16338117.
- Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome 16 (12): 942–54. doi: . PMID 16341674.