GPR109B

From Wikipedia, the free encyclopedia

G protein-coupled receptor 109B

Identifiers

GPR109B; HM74; PUMAG; Puma-g

External IDs

Gene ontology
Molecular Function:	• rhodopsin-like receptor activity • receptor activity • GTP binding • purinergic nucleotide receptor activity, G-protein coupled
Cellular Component:	• integral to plasma membrane • membrane • integral to membrane
Biological Process:	• signal transduction • G-protein coupled receptor protein signaling pathway

Orthologs

Human

Mouse

Entrez

8843

n/a

Refseq

XM_001134375 (mRNA)
XP_001134375 (protein)

n/a (mRNA)
n/a (protein)

Pubmed search

[1]

n/a

G protein-coupled receptor 109B, also known as GPR109B, is a human gene.^[1]

[edit] References

^ Entrez Gene: GPR109B G protein-coupled receptor 109B.

[edit] Further reading

Nomura H, Nielsen BW, Matsushima K (1994). "Molecular cloning of cDNAs encoding a LD78 receptor and putative leukocyte chemotactic peptide receptors.". Int. Immunol. 5 (10): 1239–49. PMID 7505609.
Zingoni A, Rocchi M, Storlazzi CT, et al. (1997). "Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor.". Genomics 42 (3): 519–23. doi:10.1006/geno.1997.4754. PMID 9205127.
Irobi J, Nelis E, Verhoeven K, et al. (2002). "Mutation analysis of 12 candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3.". J. Peripher. Nerv. Syst. 7 (2): 87–95. PMID 12090300.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Wise A, Foord SM, Fraser NJ, et al. (2003). "Molecular identification of high and low affinity receptors for nicotinic acid.". J. Biol. Chem. 278 (11): 9869–74. doi:10.1074/jbc.M210695200. PMID 12522134.
Tunaru S, Kero J, Schaub A, et al. (2003). "PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.". Nat. Med. 9 (3): 352–5. doi:10.1038/nm824. PMID 12563315.
Soga T, Kamohara M, Takasaki J, et al. (2003). "Molecular identification of nicotinic acid receptor.". Biochem. Biophys. Res. Commun. 303 (1): 364–9. PMID 12646212.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
Toulza E, Mattiuzzo NR, Galliano MF, et al.. "Large-scale identification of human genes implicated in epidermal barrier function." 8 (6): R107. doi:10.1186/gb-2007-8-6-r107. PMID 17562024.