GPHB5

From Wikipedia, the free encyclopedia

Glycoprotein hormone beta 5

Identifiers

GPHB5; GPB5; ZLUT1

External IDs

Gene ontology
Molecular Function:	• hormone activity
Cellular Component:	• extracellular region

Orthologs

Human

Mouse

Entrez

122876

n/a

Refseq

NM_145171 (mRNA)
NP_660154 (protein)

n/a (mRNA)
n/a (protein)

Pubmed search

[1]

n/a

Glycoprotein hormone beta 5, also known as GPHB5, is a human gene.^[1]

GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: GPHB5 glycoprotein hormone beta 5.

[edit] Further reading

Okada SL, Ellsworth JL, Durnam DM, et al. (2006). "A glycoprotein hormone expressed in corticotrophs exhibits unique binding properties on thyroid-stimulating hormone receptor.". Mol. Endocrinol. 20 (2): 414-25. doi:10.1210/me.2005-0270. PMID 16210345.
Sudo S, Kuwabara Y, Park JI, et al. (2005). "Heterodimeric fly glycoprotein hormone-alpha2 (GPA2) and glycoprotein hormone-beta5 (GPB5) activate fly leucine-rich repeat-containing G protein-coupled receptor-1 (DLGR1) and stimulation of human thyrotropin receptors by chimeric fly GPA2 and human GPB5.". Endocrinology 146 (8): 3596-604. doi:10.1210/en.2005-0317. PMID 15890769.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14.". Nature 421 (6923): 601-7. doi:10.1038/nature01348. PMID 12508121.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Hsu SY, Nakabayashi K, Bhalla A (2003). "Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5.". Mol. Endocrinol. 16 (7): 1538-51. PMID 12089349.
Nakabayashi K, Matsumi H, Bhalla A, et al. (2002). "Thyrostimulin, a heterodimer of two new human glycoprotein hormone subunits, activates the thyroid-stimulating hormone receptor.". J. Clin. Invest. 109 (11): 1445-52. doi:10.1172/JCI14340. PMID 12045258.