GPC6

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Glypican 6
Identifiers
Symbol(s) GPC6; MGC126288
External IDs OMIM: 604404 MGI: 1346322 HomoloGene: 55922
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10082 23888
Ensembl ENSG00000183098 ENSMUSG00000058571
Uniprot Q9Y625 Q3TP69
Refseq NM_005708 (mRNA)
NP_005699 (protein)		 NM_001079844 (mRNA)
NP_001073313 (protein)
Location Chr 13: 92.68 - 93.86 Mb Chr 14: 115.81 - 116.86 Mb
Pubmed search [1] [2]

Glypican 6, also known as GPC6, is a human gene.[1]

The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans. The glypicans have been implicated in the control of cell growth and division. Glypican 6 is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.[1]

[edit] References

  1. ^ a b Entrez Gene: GPC6 glypican 6.

[edit] Further reading

  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Veugelers M, De Cat B, Ceulemans H, et al. (1999). "Glypican-6, a new member of the glypican family of cell surface heparan sulfate proteoglycans.". J. Biol. Chem. 274 (38): 26968-77. PMID 10480909. 
  • Paine-Saunders S, Viviano BL, Saunders S (1999). "GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13.". Genomics 57 (3): 455-8. doi:10.1006/geno.1999.5793. PMID 10329016. 
  • Watanabe K, Yamada H, Yamaguchi Y (1995). "K-glypican: a novel GPI-anchored heparan sulfate proteoglycan that is highly expressed in developing brain and kidney.". J. Cell Biol. 130 (5): 1207-18. PMID 7657705. 
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