GORASP2

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Golgi reassembly stacking protein 2, 55kDa
Identifiers
Symbol(s) GORASP2; DKFZP434D156; FLJ13139; GOLPH6; GRASP55; GRS2; p59
External IDs OMIM: 608693 MGI: 2135962 HomoloGene: 9180
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 26003 70231
Ensembl ENSG00000115806 ENSMUSG00000014959
Uniprot Q9H8Y8 Q3TG07
Refseq NM_015530 (mRNA)
NP_056345 (protein)		 NM_027352 (mRNA)
NP_081628 (protein)
Location Chr 2: 171.49 - 171.53 Mb Chr 2: 70.46 - 70.49 Mb
Pubmed search [1] [2]

Golgi reassembly stacking protein 2, 55kDa, also known as GORASP2, is a human gene.[1]

The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in establishing the stacked structure of the Golgi apparatus.[1]

[edit] References

  1. ^ a b Entrez Gene: GORASP2 golgi reassembly stacking protein 2, 55kDa.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Shorter J, Watson R, Giannakou ME, et al. (1999). "GRASP55, a second mammalian GRASP protein involved in the stacking of Golgi cisternae in a cell-free system.". EMBO J. 18 (18): 4949–60. doi:10.1093/emboj/18.18.4949. PMID 10487747. 
  • Kuo A, Zhong C, Lane WS, Derynck R (2001). "Transmembrane transforming growth factor-alpha tethers to the PDZ domain-containing, Golgi membrane-associated protein p59/GRASP55.". EMBO J. 19 (23): 6427–39. doi:10.1093/emboj/19.23.6427. PMID 11101516. 
  • Jesch SA, Lewis TS, Ahn NG, Linstedt AD (2001). "Mitotic phosphorylation of Golgi reassembly stacking protein 55 by mitogen-activated protein kinase ERK2.". Mol. Biol. Cell 12 (6): 1811–7. PMID 11408587. 
  • Short B, Preisinger C, Körner R, et al. (2002). "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic.". J. Cell Biol. 155 (6): 877–83. doi:10.1083/jcb.200108079. PMID 11739401. 
  • Barr FA, Preisinger C, Kopajtich R, Körner R (2002). "Golgi matrix proteins interact with p24 cargo receptors and aid their efficient retention in the Golgi apparatus.". J. Cell Biol. 155 (6): 885–91. doi:10.1083/jcb.200108102. PMID 11739402. 
  • Lane JD, Lucocq J, Pryde J, et al. (2002). "Caspase-mediated cleavage of the stacking protein GRASP65 is required for Golgi fragmentation during apoptosis.". J. Cell Biol. 156 (3): 495–509. doi:10.1083/jcb.200110007. PMID 11815631. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Gandhi TK, Zhong J, Mathivanan S, et al. (2006). "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets.". Nat. Genet. 38 (3): 285–93. doi:10.1038/ng1747. PMID 16501559. 
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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