GMPPB

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GDP-mannose pyrophosphorylase B
Identifiers
Symbol(s) GMPPB; KIAA1851
External IDs MGI: 2660880 HomoloGene: 5578
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 29925 331026
Ensembl ENSG00000173540 ENSMUSG00000070284
Refseq NM_013334 (mRNA)
NP_037466 (protein)		 NM_177910 (mRNA)
NP_808578 (protein)
Location Chr 3: 49.73 - 49.74 Mb Chr 9: 107.91 - 107.91 Mb
Pubmed search [1] [2]

GDP-mannose pyrophosphorylase B, also known as GMPPB, is a human gene.[1]

This gene is thought to encode a GDP-mannose pyrophosphorylase. This enzyme catalyzes the reaction which converts mannose-1-phosphate and GTP to GDP-mannose which is involved in the production of N-linked oligosaccharides. The gene encodes two transcript variants.[1]

[edit] References

  1. ^ a b Entrez Gene: GMPPB GDP-mannose pyrophosphorylase B.

[edit] Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Ono T, Sekino-Suzuki N, Kikkawa Y, et al. (2003). "Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons.". J. Neurosci. 23 (13): 5887–96. PMID 12843293. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Nagase T, Nakayama M, Nakajima D, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 8 (2): 85–95. PMID 11347906. 
  • Ning B, Elbein AD (2001). "Cloning, expression and characterization of the pig liver GDP-mannose pyrophosphorylase. Evidence that GDP-mannose and GDP-Glc pyrophosphorylases are different proteins.". Eur. J. Biochem. 267 (23): 6866–74. PMID 11082198. 
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