Glycosulfatase

From Wikipedia, the free encyclopedia

In enzymology, a glycosulfatase (EC 3.1.6.3) is an enzyme that catalyzes the chemical reaction

D-glucose 6-sulfate + H₂O D-glucose + sulfate

Thus, the two substrates of this enzyme are D-glucose 6-sulfate and H₂O, whereas its two products are D-glucose and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is sugar-sulfate sulfohydrolase. This enzyme is also called glucosulfatase. This enzyme participates in glycolysis / gluconeogenesis.

[edit] References

• IUBMB entry for 3.1.6.3
• BRENDA references for 3.1.6.3 (Recommended.)
• PubMed references for 3.1.6.3
• PubMed Central references for 3.1.6.3
• Google Scholar references for 3.1.6.3
• Dodgson KS (1961). "Glycosulphatase: observations on the activity of partially purified preparations towards the sulphate esters of certain monosaccharides and steroids". Biochem. J. 78: 324–333. 
• Egami F and Takahaski N (1955). "Syntheses of adenosinesulfuric acids". Bull. Chem. Soc. Jpn. 28: 666–668. 
• Roy, AB (1960). "The synthesis and hydrolysis of sulfate esters". Adv. Enzymol. Relat. Subj. Biochem. 22: 205–235. 

[edit] External links

The CAS registry number for this enzyme class is 9025-61-0.

• IUBMB entry for 3.1.6.3

• KEGG entry for 3.1.6.3

• BRENDA entry for 3.1.6.3

• NiceZyme view of 3.1.6.3

• EC2PDB: PDB structures for 3.1.6.3

• PRIAM entry for 3.1.6.3

• PUMA2 entry for 3.1.6.3

• IntEnz: Integrated Enzyme entry for 3.1.6.3

• MetaCyc entry for 3.1.6.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047966: glycosulfatase

• AMIGO entry for GO code 0047966: glycosulfatase