Glycosaminoglycan galactosyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a glycosaminoglycan galactosyltransferase (EC 2.4.1.74) is an enzyme that catalyzes the chemical reaction

UDP-galactose + glycosaminoglycan UDP + D-galactosylglycosaminoglycan

Thus, the two substrates of this enzyme are UDP-galactose and glycosaminoglycan, whereas its two products are UDP and D-galactosylglycosaminoglycan.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:glycosaminoglycan D-galactosyltransferase. This enzyme is also called uridine diphosphogalactose-mucopolysaccharide galactosyltransferase.

[edit] References

• IUBMB entry for 2.4.1.74
• BRENDA references for 2.4.1.74 (Recommended.)
• PubMed references for 2.4.1.74
• PubMed Central references for 2.4.1.74
• Google Scholar references for 2.4.1.74
• Sussman M and Osborn MJ (1964). "UDP-glucose polysaccharide transferase in the cellular slime mold Dictyostelium discoideum: appearance and dissappearance of activity during cell differentiation". Proc. Natl. Acad. Sci. USA 52: 81–87. doi:10.1073/pnas.52.1.81. 

[edit] External links

The CAS registry number for this enzyme class is 51004-28-5.

• IUBMB entry for 2.4.1.74

• KEGG entry for 2.4.1.74

• BRENDA entry for 2.4.1.74

• NiceZyme view of 2.4.1.74

• EC2PDB: PDB structures for 2.4.1.74

• PRIAM entry for 2.4.1.74

• PUMA2 entry for 2.4.1.74

• IntEnz: Integrated Enzyme entry for 2.4.1.74

• MetaCyc entry for 2.4.1.74

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047271: glycosaminoglycan galactosyltransferase

• AMIGO entry for GO code 0047271: glycosaminoglycan galactosyltransferase