Glycoprotein O-fatty-acyltransferase

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In enzymology, a glycoprotein O-fatty-acyltransferase (EC 2.3.1.142) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + mucus glycoprotein CoA + O-palmitoylglycoprotein

Thus, the two substrates of this enzyme are palmitoyl-CoA and mucus glycoprotein, whereas its two products are CoA and O-palmitoylglycoprotein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is fatty-acyl-CoA:mucus-glycoprotein fatty-acyltransferase. This enzyme is also called protein acyltransferase.

[edit] References

• IUBMB entry for 2.3.1.142
• BRENDA references for 2.3.1.142 (Recommended.)
• PubMed references for 2.3.1.142
• PubMed Central references for 2.3.1.142
• Google Scholar references for 2.3.1.142
• Kasinathan C, Grzelinska E, Okazaki K, Slomiany BL, Slomiany A (1990). "Purification of protein fatty acyltransferase and determination of its distribution and topology". J. Biol. Chem. 265: 5139–44. PMID 2318887. 

[edit] External links

The CAS registry number for this enzyme class is 122191-29-1.

• IUBMB entry for 2.3.1.142

• KEGG entry for 2.3.1.142

• BRENDA entry for 2.3.1.142

• NiceZyme view of 2.3.1.142

• EC2PDB: PDB structures for 2.3.1.142

• PRIAM entry for 2.3.1.142

• PUMA2 entry for 2.3.1.142

• IntEnz: Integrated Enzyme entry for 2.3.1.142

• MetaCyc entry for 2.3.1.142

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047965: glycoprotein O-fatty-acyltransferase

• AMIGO entry for GO code 0047965: glycoprotein O-fatty-acyltransferase