Glycine dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a glycine dehydrogenase (EC 1.4.1.10) is an enzyme that catalyzes the chemical reaction

glycine + H₂O + NAD⁺ glyoxylate + NH₃ + NADH + H⁺

The 3 substrates of this enzyme are glycine, H₂O, and NAD⁺, whereas its 4 products are glyoxylate, NH₃, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycine:NAD+ oxidoreductase (deaminating).

[edit] References

• IUBMB entry for 1.4.1.10
• BRENDA references for 1.4.1.10 (Recommended.)
• PubMed references for 1.4.1.10
• PubMed Central references for 1.4.1.10
• Google Scholar references for 1.4.1.10
• GOLDMAN DS, WAGNER MJ (1962). "Enzyme systems in the mycobacteria. XIII. Glycine dehydrogenase and the glyoxylic acid cycle". Biochim. Biophys. Acta. 65: 297–306. doi:10.1016/0006-3002(62)91048-X. PMID 13948749. 

[edit] External links

The CAS registry number for this enzyme class is 37255-40-6.

• IUBMB entry for 1.4.1.10

• KEGG entry for 1.4.1.10

• BRENDA entry for 1.4.1.10

• NiceZyme view of 1.4.1.10

• EC2PDB: PDB structures for 1.4.1.10

• PRIAM entry for 1.4.1.10

• PUMA2 entry for 1.4.1.10

• IntEnz: Integrated Enzyme entry for 1.4.1.10

• MetaCyc entry for 1.4.1.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047960: glycine dehydrogenase

• AMIGO entry for GO code 0047960: glycine dehydrogenase