Glycerol 2-dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia

In enzymology, a glycerol 2-dehydrogenase (NADP+) (EC 1.1.1.156) is an enzyme that catalyzes the chemical reaction

glycerol + NADP⁺ glycerone + NADPH + H⁺

Thus, the two substrates of this enzyme are glycerol and NADP⁺, whereas its 3 products are glycerone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycerol:NADP+ 2-oxidoreductase (glycerone-forming). Other names in common use include dihydroxyacetone reductase, dihydroxyacetone (reduced nicotinamide adenine dinucleotide, phosphate) reductase, dihydroxyacetone reductase (NADPH), DHA oxidoreductase, and glycerol 2-dehydrogenase (NADP+). This enzyme participates in glycerolipid metabolism.

[edit] References

• IUBMB entry for 1.1.1.156
• BRENDA references for 1.1.1.156 (Recommended.)
• PubMed references for 1.1.1.156
• PubMed Central references for 1.1.1.156
• Google Scholar references for 1.1.1.156
• Ben-Amotz A, Avron M (1973). "NADP specific dihydroxyacetone reductase from Dunaliella parva". FEBS. Lett. 29: 153–5. doi:10.1016/0014-5793(73)80548-4. PMID 4146296. 

[edit] External links

The CAS registry number for this enzyme class is 39342-20-6.

• IUBMB entry for 1.1.1.156

• KEGG entry for 1.1.1.156

• BRENDA entry for 1.1.1.156

• NiceZyme view of 1.1.1.156

• EC2PDB: PDB structures for 1.1.1.156

• PRIAM entry for 1.1.1.156

• PUMA2 entry for 1.1.1.156

• IntEnz: Integrated Enzyme entry for 1.1.1.156

• MetaCyc entry for 1.1.1.156

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047953: glycerol 2-dehydrogenase (NADP+)

• AMIGO entry for GO code 0047953: glycerol 2-dehydrogenase (NADP+)