Glutathione thiolesterase

From Wikipedia, the free encyclopedia

In enzymology, a glutathione thiolesterase (EC 3.1.2.7) is an enzyme that catalyzes the chemical reaction

S-acylglutathione + H₂O glutathione + a carboxylate

Thus, the two substrates of this enzyme are S-acylglutathione and H₂O, whereas its two products are glutathione and carboxylate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is S-acylglutathione hydrolase. This enzyme is also called citryl-glutathione thioesterhydrolase.

[edit] References

• IUBMB entry for 3.1.2.7
• BRENDA references for 3.1.2.7 (Recommended.)
• PubMed references for 3.1.2.7
• PubMed Central references for 3.1.2.7
• Google Scholar references for 3.1.2.7
• KIELLEY WW, BRADLEY LB (1954). "Glutathione thiolesterase". J. Biol. Chem. 206: 327–33. PMID 13130552. 

[edit] External links

The CAS registry number for this enzyme class is 9025-99-4.

• IUBMB entry for 3.1.2.7

• KEGG entry for 3.1.2.7

• BRENDA entry for 3.1.2.7

• NiceZyme view of 3.1.2.7

• EC2PDB: PDB structures for 3.1.2.7

• PRIAM entry for 3.1.2.7

• PUMA2 entry for 3.1.2.7

• IntEnz: Integrated Enzyme entry for 3.1.2.7

• MetaCyc entry for 3.1.2.7

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047951: glutathione thiolesterase

• AMIGO entry for GO code 0047951: glutathione thiolesterase