Glutamate racemase

From Wikipedia, the free encyclopedia

In enzymology, a glutamate racemase (EC 5.1.1.3) is an enzyme that catalyzes the chemical reaction

L-glutamate D-glutamate

Hence, this enzyme has one substrate, L-glutamate, and one product, D-glutamate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is glutamate racemase. This enzyme participates in glutamate metabolism and d-glutamine and d-glutamate metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 17 structures have been solved for this class of enzymes, with PDB accession codes 1B73, 1B74, 1ZUW, 2DWU, 2GZM, 2JFN, 2JFO, 2JFP, 2JFQ, 2JFU, 2JFV, 2JFW, 2JFX, 2JFZ, 2OHG, 2OHO, and 2OHV.

[edit] References

• IUBMB entry for 5.1.1.3
• BRENDA references for 5.1.1.3 (Recommended.)
• PubMed references for 5.1.1.3
• PubMed Central references for 5.1.1.3
• Google Scholar references for 5.1.1.3
• GLASER L (1960). "Glutamic acid racemase from Lactobacillus arabinosus". J. Biol. Chem. 235: 2095–8. PMID 13828348. 

[edit] External links

The CAS registry number for this enzyme class is 9024-08-2.

• IUBMB entry for 5.1.1.3

• KEGG entry for 5.1.1.3

• BRENDA entry for 5.1.1.3

• NiceZyme view of 5.1.1.3

• EC2PDB: PDB structures for 5.1.1.3

• PRIAM entry for 5.1.1.3

• PUMA2 entry for 5.1.1.3

• IntEnz: Integrated Enzyme entry for 5.1.1.3

• MetaCyc entry for 5.1.1.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008881: glutamate racemase

• AMIGO entry for GO code 0008881: glutamate racemase