Glutamate-ethylamine ligase

From Wikipedia, the free encyclopedia

In enzymology, a glutamate-ethylamine ligase (EC 6.3.1.6) is an enzyme that catalyzes the chemical reaction

ATP + L-glutamate + ethylamine ADP + phosphate + N₅-ethyl-L-glutamine

The 3 substrates of this enzyme are ATP, L-glutamate, and ethylamine, whereas its 3 products are ADP, phosphate, and N5-ethyl-L-glutamine.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). The systematic name of this enzyme class is L-glutamate:ethylamine ligase (ADP-forming). Other names in common use include N5-ethyl-L-glutamine synthetase, theanine synthetase, and N5-ethylglutamine synthetase.

[edit] References

• IUBMB entry for 6.3.1.6
• BRENDA references for 6.3.1.6 (Recommended.)
• PubMed references for 6.3.1.6
• PubMed Central references for 6.3.1.6
• Google Scholar references for 6.3.1.6
• Sasaoka K and Kito M (1964). "Synthesis of theanine by tea seedling homogenate". Agric. Biol. Chem. 28: 313–317. 
• Sasaoka K, Kito M and Inagaki H (1963). "Studies on the biosynthesis of theanine in tea seedlings. Synthesis of theanine by the homogenate of tea seedlings". Agric. Biol. Chem. 27: 467–468. 
• Sasaoka K, Kito M and Onishi Y (1965). "Some properties of the theanine synthesizing enzyme in tea seedlings". Agric. Biol. Chem. 29: 984–988. 

[edit] External links

The CAS registry number for this enzyme class is 62213-31-4.

• IUBMB entry for 6.3.1.6

• KEGG entry for 6.3.1.6

• BRENDA entry for 6.3.1.6

• NiceZyme view of 6.3.1.6

• EC2PDB: PDB structures for 6.3.1.6

• PRIAM entry for 6.3.1.6

• PUMA2 entry for 6.3.1.6

• IntEnz: Integrated Enzyme entry for 6.3.1.6

• MetaCyc entry for 6.3.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047942: glutamate-ethylamine ligase

• AMIGO entry for GO code 0047942: glutamate-ethylamine ligase