Glucuronokinase

From Wikipedia, the free encyclopedia

In enzymology, a glucuronokinase (EC 2.7.1.43) is an enzyme that catalyzes the chemical reaction

ATP + D-glucuronate ADP + 1-phospho-alpha-D-glucuronate

Thus, the two substrates of this enzyme are ATP and D-glucuronate, whereas its two products are ADP and 1-phospho-alpha-D-glucuronate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-glucuronate 1-phosphotransferase. Other names in common use include glucuronokinase (phosphorylating), and glucurono-glucuronokinase. This enzyme participates in pentose and glucuronate interconversions and ascorbate and aldarate metabolism.

[edit] References

• IUBMB entry for 2.7.1.43
• BRENDA references for 2.7.1.43 (Recommended.)
• PubMed references for 2.7.1.43
• PubMed Central references for 2.7.1.43
• Google Scholar references for 2.7.1.43
• Neufeld EF, Feingold DS and Hassid WZ (1959). "Enzymic phosphorylation of D-glucuronic acid by extracts from seedlings of Phaseolus aureus". Arch. Biochem. Biophys. 83: 96–100. 

[edit] External links

The CAS registry number for this enzyme class is 9026-62-4.

• IUBMB entry for 2.7.1.43

• KEGG entry for 2.7.1.43

• BRENDA entry for 2.7.1.43

• NiceZyme view of 2.7.1.43

• EC2PDB: PDB structures for 2.7.1.43

• PRIAM entry for 2.7.1.43

• PUMA2 entry for 2.7.1.43

• IntEnz: Integrated Enzyme entry for 2.7.1.43

• MetaCyc entry for 2.7.1.43

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047940: glucuronokinase

• AMIGO entry for GO code 0047940: glucuronokinase