Glucuronate-1-phosphate uridylyltransferase
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In enzymology, a glucuronate-1-phosphate uridylyltransferase (EC 2.7.7.44) is an enzyme that catalyzes the chemical reaction
- UTP + 1-phospho-alpha-D-glucuronate diphosphate + UDP-glucuronate
Thus, the two substrates of this enzyme are UTP and 1-phospho-alpha-D-glucuronate, whereas its two products are diphosphate and UDP-glucuronate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:1-phospho-alpha-D-glucuronate uridylyltransferase. Other names in common use include UDP-glucuronate pyrophosphorylase, UDP-D-glucuronic acid pyrophosphorylase, UDP-glucuronic acid pyrophosphorylase, and uridine diphosphoglucuronic pyrophosphorylase. This enzyme participates in pentose and glucuronate interconversions and ascorbate and aldarate metabolism.
[edit] References
- IUBMB entry for 2.7.7.44
- BRENDA references for 2.7.7.44 (Recommended.)
- PubMed references for 2.7.7.44
- PubMed Central references for 2.7.7.44
- Google Scholar references for 2.7.7.44
- Roberts RM (1971). "The formation of uridine diphosphate-glucuronic acid in plants Uridine diphosphate-glucuronic acid pyrophosphorylase from barley seedlings". J. Biol. Chem. 246: 4995–5002. PMID 5570433.
[edit] External links
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- The CAS registry number for this enzyme class is 52228-05-4.