Glucose dehydrogenase (acceptor)

From Wikipedia, the free encyclopedia

In enzymology, a glucose dehydrogenase (acceptor) (EC 1.1.99.10) is an enzyme that catalyzes the chemical reaction

D-glucose + acceptor D-glucono-1,5-lactone + reduced acceptor

Thus, the two substrates of this enzyme are D-glucose and acceptor, whereas its two products are D-glucono-1,5-lactone and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:acceptor 1-oxidoreductase. Other names in common use include glucose dehydrogenase (Aspergillus), glucose dehydrogenase (decarboxylating), and D-glucose:(acceptor) 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.1.99.10
• BRENDA references for 1.1.99.10 (Recommended.)
• PubMed references for 1.1.99.10
• PubMed Central references for 1.1.99.10
• Google Scholar references for 1.1.99.10
• Bak TG (1967). "Studies on glucose dehydrogenase of Aspergillus oryzae. II Purification and physical and chemical properties". Biochim. Biophys. Acta. 139: 277–93. PMID 6034674. 

[edit] External links

The CAS registry number for this enzyme class is 37250-84-3.

• IUBMB entry for 1.1.99.10

• KEGG entry for 1.1.99.10

• BRENDA entry for 1.1.99.10

• NiceZyme view of 1.1.99.10

• EC2PDB: PDB structures for 1.1.99.10

• PRIAM entry for 1.1.99.10

• PUMA2 entry for 1.1.99.10

• IntEnz: Integrated Enzyme entry for 1.1.99.10

• MetaCyc entry for 1.1.99.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004344: glucose dehydrogenase (acceptor)

• AMIGO entry for GO code 0004344: glucose dehydrogenase (acceptor)