Glucose 1-dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia

In enzymology, a glucose 1-dehydrogenase (NADP+) (EC 1.1.1.119) is an enzyme that catalyzes the chemical reaction

D-glucose + NADP⁺ D-glucono-1,5-lactone + NADPH + H⁺

Thus, the two substrates of this enzyme are D-glucose and NADP⁺, whereas its 3 products are D-glucono-1,5-lactone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glucose:NADP+ 1-oxidoreductase. Other names in common use include nicotinamide adenine dinucleotide phosphate-linked aldohexose, dehydrogenase, NADP+-linked aldohexose dehydrogenase, NADP+-dependent glucose dehydrogenase, and glucose 1-dehydrogenase (NADP+).

[edit] References

• IUBMB entry for 1.1.1.119
• BRENDA references for 1.1.1.119 (Recommended.)
• PubMed references for 1.1.1.119
• PubMed Central references for 1.1.1.119
• Google Scholar references for 1.1.1.119
• Adachi O and Ameyama M (1982). "D-Glucose dehydrogenase from Gluconobacter suboxydans". Methods Enzymol. 89: 159–163. 
• Avigad G, Alroy Y, Englard S (1968). "Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogeanse from Gluconobacter cerinus". J. Biol. Chem. 243: 1936–41. PMID 4384672. 

[edit] External links

The CAS registry number for this enzyme class is 37250-50-3.

• IUBMB entry for 1.1.1.119

• KEGG entry for 1.1.1.119

• BRENDA entry for 1.1.1.119

• NiceZyme view of 1.1.1.119

• EC2PDB: PDB structures for 1.1.1.119

• PRIAM entry for 1.1.1.119

• PUMA2 entry for 1.1.1.119

• IntEnz: Integrated Enzyme entry for 1.1.1.119

• MetaCyc entry for 1.1.1.119

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047935: glucose 1-dehydrogenase (NADP+)

• AMIGO entry for GO code 0047935: glucose 1-dehydrogenase (NADP+)