Glucose-fructose oxidoreductase

From Wikipedia, the free encyclopedia

In enzymology, a glucose-fructose oxidoreductase (EC 1.1.99.28) is an enzyme that catalyzes the chemical reaction

D-glucose + D-fructose $\rightleftharpoons$ D-gluconolactone + D-glucitol

Thus, the two substrates of this enzyme are D-glucose and D-fructose, whereas its two products are D-gluconolactone and D-glucitol.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:D-fructose oxidoreductase.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1H6A, 1H6B, 1H6C, 1H6D, 1OFG, 1RYD, and 1RYE.

[edit] References

IUBMB entry for 1.1.99.28
BRENDA references for 1.1.99.28 (Recommended.)
PubMed references for 1.1.99.28
PubMed Central references for 1.1.99.28
Google Scholar references for 1.1.99.28
Zachariou M and Scopes RK (1986). "Glucose-fructose oxidoreductase: a new enzyme isolated from Zymomonas mobilis that is responsible for sorbitol production". J. Bacteriol. 167: 863–869.
Hardman MJ, Scopes RK (1988). "The kinetics of glucose-fructose oxidoreductase from Zymomonas mobilis". Eur. J. Biochem. 173: 203–9. doi:10.1111/j.1432-1033.1988.tb13985.x. PMID 3356190.
Kanagasundaram V, Scopes RK (1992). "Cloning, sequence analysis, and expression of the structural gene encoding glucose-fructose oxidoreductase from Zymomonas mobilis". J. Bacteriol. 174: 1439–47. PMID 1537789.