Glucose-6-phosphate 1-epimerase

From Wikipedia, the free encyclopedia

In enzymology, a glucose-6-phosphate 1-epimerase (EC 5.1.3.15) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 6-phosphate beta-D-glucose 6-phosphate

Hence, this enzyme has one substrate, alpha-D-glucose 6-phosphate, and one product, beta-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is D-glucose-6-phosphate 1-epimerase. This enzyme participates in glycolysis / gluconeogenesis.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 2CIQ, 2CIR, and 2CIS.

[edit] References

• IUBMB entry for 5.1.3.15
• BRENDA references for 5.1.3.15 (Recommended.)
• PubMed references for 5.1.3.15
• PubMed Central references for 5.1.3.15
• Google Scholar references for 5.1.3.15
• Wurster B, Hess B (1972). "Glucose-6-phosphate-1-epimerase from baker's yeast. A new enzyme". FEBS. Lett. 23: 341–344. PMID 11946648. 

[edit] External links

The CAS registry number for this enzyme class is 37259-65-7.

• IUBMB entry for 5.1.3.15

• KEGG entry for 5.1.3.15

• BRENDA entry for 5.1.3.15

• NiceZyme view of 5.1.3.15

• EC2PDB: PDB structures for 5.1.3.15

• PRIAM entry for 5.1.3.15

• PUMA2 entry for 5.1.3.15

• IntEnz: Integrated Enzyme entry for 5.1.3.15

• MetaCyc entry for 5.1.3.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047938: glucose-6-phosphate 1-epimerase

• AMIGO entry for GO code 0047938: glucose-6-phosphate 1-epimerase