Glucose-1-phosphate guanylyltransferase

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In enzymology, a glucose-1-phosphate guanylyltransferase (EC 2.7.7.34) is an enzyme that catalyzes the chemical reaction

GTP + alpha-D-glucose 1-phosphate diphosphate + GDP-glucose

Thus, the two substrates of this enzyme are GTP and alpha-D-glucose 1-phosphate, whereas its two products are diphosphate and GDP-glucose.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is GTP:alpha-D-glucose-1-phosphate guanylyltransferase. Other names in common use include GDP glucose pyrophosphorylase, and guanosine diphosphoglucose pyrophosphorylase. This enzyme participates in starch and sucrose metabolism.

[edit] References

• IUBMB entry for 2.7.7.34
• BRENDA references for 2.7.7.34 (Recommended.)
• PubMed references for 2.7.7.34
• PubMed Central references for 2.7.7.34
• Google Scholar references for 2.7.7.34
• Danishefsky I, Heritier-Watkins O (1967). "Nucleoside diphosphate glucose pyrophosphorylases in mast cell tumors". Biochim. Biophys. Acta. 139: 349–57. PMID 6034677. 

[edit] External links

The CAS registry number for this enzyme class is 9033-13-0.

• IUBMB entry for 2.7.7.34

• KEGG entry for 2.7.7.34

• BRENDA entry for 2.7.7.34

• NiceZyme view of 2.7.7.34

• EC2PDB: PDB structures for 2.7.7.34

• PRIAM entry for 2.7.7.34

• PUMA2 entry for 2.7.7.34

• IntEnz: Integrated Enzyme entry for 2.7.7.34

• MetaCyc entry for 2.7.7.34

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047344: glucose-1-phosphate guanylyltransferase

• AMIGO entry for GO code 0047344: glucose-1-phosphate guanylyltransferase