Glucose-1-phosphate cytidylyltransferase
From Wikipedia, the free encyclopedia
In enzymology, a glucose-1-phosphate cytidylyltransferase (EC 2.7.7.33) is an enzyme that catalyzes the chemical reaction
- CTP + alpha-D-glucose 1-phosphate
diphosphate + CDP-glucose
Thus, the two substrates of this enzyme are CTP and alpha-D-glucose 1-phosphate, whereas its two products are diphosphate and CDP-glucose.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is CTP:alpha-D-glucose-1-phosphate cytidylyltransferase. Other names in common use include CDP glucose pyrophosphorylase, cytidine diphosphoglucose pyrophosphorylase, cytidine diphosphate glucose pyrophosphorylase, cytidine diphosphate-D-glucose pyrophosphorylase, and CTP:D-glucose-1-phosphate cytidylyltransferase. This enzyme participates in starch and sucrose metabolism and nucleotide sugars metabolism.
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[edit] Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1TZF and 1WVC.
[edit] References
- IUBMB entry for 2.7.7.33
- BRENDA references for 2.7.7.33 (Recommended.)
- PubMed references for 2.7.7.33
- PubMed Central references for 2.7.7.33
- Google Scholar references for 2.7.7.33
- MAYER RM, GINSBURG V (1965). "PURIFICATION AND PROPERTIES OF CYTIDINE DIPHOSPHATE D-GLUCOSE PYROPHOSPHORYLASE FROM SALMONELLA PARATYPHI A". J. Biol. Chem. 240: 1900–4. PMID 14299608.
[edit] External links
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- The CAS registry number for this enzyme class is 9027-10-5.
[edit] Gene Ontology (GO) codes
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