Glucose-1-phosphate

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Glucose-1-phosphate


Identifiers
CAS number	[59-56-3]
PubChem	65533
MeSH	glucose-1-phosphate
Properties
Molecular formula	C6H13O9P
Molar mass	260.136
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.

1 Reactions
- 1.1 Catabolic
- 1.2 Anabolic
2 See also
3 External links

[edit] Reactions

[edit] Catabolic

In glycogenolysis, it is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure.

To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell mebrane and so is marked for intracellular catabolism.

[edit] Anabolic

In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. It can then return to the greater glycogen structure via glycogen synthase.