Glucose-1-phosphatase

From Wikipedia, the free encyclopedia

In enzymology, a glucose-1-phosphatase (EC 3.1.3.10) is an enzyme that catalyzes the chemical reaction

alpha-D-glucose 1-phosphate + H₂O D-glucose + phosphate

Thus, the two substrates of this enzyme are alpha-D-glucose 1-phosphate and H₂O, whereas its two products are D-glucose and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is alpha-D-glucose-1-phosphate phosphohydrolase. This enzyme participates in glycolysis / gluconeogenesis.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1NT4.

[edit] References

• IUBMB entry for 3.1.3.10
• BRENDA references for 3.1.3.10 (Recommended.)
• PubMed references for 3.1.3.10
• PubMed Central references for 3.1.3.10
• Google Scholar references for 3.1.3.10
• FAULKNER P (1955). "A hexose-1-phosphatase in silkworm blood". Biochem. J. 60: 590–6. PMID 13249953. 
• Turner DH and Turner JF (1960). "The hydrolysis of glucose monophosphates by a phosphatase preparation from pea seeds". Biochem. J. 74: 486–491. 

[edit] External links

The CAS registry number for this enzyme class is 9001-38-1.

• IUBMB entry for 3.1.3.10

• KEGG entry for 3.1.3.10

• BRENDA entry for 3.1.3.10

• NiceZyme view of 3.1.3.10

• EC2PDB: PDB structures for 3.1.3.10

• PRIAM entry for 3.1.3.10

• PUMA2 entry for 3.1.3.10

• IntEnz: Integrated Enzyme entry for 3.1.3.10

• MetaCyc entry for 3.1.3.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008877: glucose-1-phosphatase

• AMIGO entry for GO code 0008877: glucose-1-phosphatase