Talk:Glioblastoma multiforme
From Wikipedia, the free encyclopedia
 |
This article is within the scope of WikiProject Neurology. Please visit the project page for details or ask questions at the talk page. |
| Start | This page has been rated as Start-Class on the quality assessment scale |
| Mid | This article has been rated as Mid-importance on the importance assessment scale |
 |
This article is within the scope of WikiProject Medicine. Please visit the project page for details or ask questions at the doctor's mess. |
| B | This page has been rated as B-Class on the quality assessment scale |
| Mid | This article has been rated as mid-importance on the importance assessment scale |
Contents |
[edit] One
One thing: I don't know that glioblastoma has a tendency for a "butterfly", bihemisphere quality. This certain does happen from time to time, but its not exclusive to GBM, nor is it necessarily common.
[edit] Causes?
Can somebody add a section about causes of such tumours, or link to such information?
- Primarily the causes are unknown, but they're getting closer. Details here under "Causes". --Arcadian 18:04, 14 January 2006 (UTC)
- Terrence McKenna was an author of several books and was also known as someone who was a 'DMT' explorer and regular psilicobyn user. I admire the guy, but what is the likelihood this was environmentally induced by some substance (possibly by accident or contamination of false fungi genus. IE: Fly Agaric is harmless (in comparison to alcohol), but it is possible to consume other hallucinogenic mushrooms which look identical and are poisonous). I can't find anything about this but it makes you think? --213.106.102.178 21:56, 14 June 2006 (UTC)
[edit] Chloroquine
When you're stuck, try antimalarials[1]. JFW | T@lk 23:53, 6 March 2006 (UTC)
[edit] Probably a Stupid Question But...
What defines glioblastoma multiforme? I know that they're a very serious form of brain tumor with a poor survival rate etc. from the article but I'm still a little confused what makes a brain tumor glioblastoma multiforme. Since I've read that brain tumors do not often metastasize I'm not sure what factors influence the severity of a tumor. The article is obviously meant for someone with a little more background knowledge but if anyone knew a way to explain this I'd be extremely thankful if you could clear this up. Sorry for my ignorance and thank you for any help offered. Blademaster 02:35, 13 October 2006 (UTC)
[edit] Long Term Survivors
Has anyone more information on the mentioned long term survivors and Dr. Ben Williams? To me this sounds a bit strange and like snake oil - but I would be glad to be proved wrong.
[edit] Long Term Survivor
My ex-husband was diagnosed with GBM IV in December or 2000...I am glad to report that he is still alive...and living a somewhat normal life. He is in an assisted living facility, however he got a part time job, plays golf, goes out with friends, etc. Just 2 short years ago he was knocking on death's door. In a nursing home, unable to feed himself, walk, talk, in diapers, etc. He was diagnosed at age 39.
(Jap524 18:46, 13 June 2007 (UTC))
[edit] Temozolomide
It's my impression that temozolomide (Temodar) is now the chemical agent of choice for initial chemotherapy, and that the other chemical agents mentioned such as carboplatin are no longer considered desirable treatments for GBM. However I am strictly a layman. It would be good if someone with current expertise would review this part of the entry and update it if appropriate.
67.39.204.192 21:47, 15 September 2007 (UTC)
I was recently diagnosed with GBM and my understanding is that this is in fact correct. As shown in the National Cancer Institute article (http://www.cancer.gov/clinicaltrials/results/glioblastoma0604) the PCV regimen has been replaced by temozolomide (Temodar) as the current standard of care. The Temodar has been found to be effective in getting through the blood brain barrier and has significantly less side effects. The NCI article notes an increase in the 2 year survival rate for GBM of 10% (radiation alone) to 26%. (radiation + Temodar).
It would be much appreciated if this Wiki could be updated to the current "standard of care" for GBM
Craig Farnsworth cfarnsworth9@gmail.com 67.39.204.192 21:47, 15 September 2007 (UTC)
- I have added some references to the "Treatment" section to address this. (However, that section is still poorly organized. It would probably be best to delete the statements that can't be specifically tied to a source, and then split the experimental treatments from the current standard of care under a separate heading.) --Arcadian 23:47, 15 September 2007 (UTC)
[edit] New Treatment Reported
I saw an article in Physics Today regarding this cancer, and an experimental treatment using low frequency electric fields. Take a look here (http://ptonline.aip.org/journals/doc/PHTOAD-ft/vol_60/iss_8/19_1.shtml) for details. Perhaps this should be referenced in a section in the article page, but I'm a WikiNewbie so I'll let someone more competent do that. MGF mgforbes@mindspring.com 12.24.60.12 05:27, 27 September 2007 (UTC)
[edit] Using viruses to attack tumor
Some refs to a newly published research: http://www.technologyreview.com/Biotech/20363/ http://www.jneurosci.org/cgi/content/abstract/28/8/1882
I'm not an editor so wouldn't know how to properly update the article with this interesting new research. —Preceding unsigned comment added by 89.1.86.245 (talk) 22:10, 3 March 2008 (UTC)
[edit] External links
Wikipedia's external links policy and the specific guidelines for medicine-related articles do not permit the inclusion of external links to non-encyclopedic material, particularly including: patient support groups, personal experience/survivor stories, internet chat boards, e-mail discussion groups, recruiters for clinical trials, healthcare providers, or similar pages.
Wikipedia is an encyclopedia, not an advertising opportunity or a support group for patients or their families. Please do not re-insert links that do not conform to the standard rules.
External links are not required in Wikipedia articles. They are permitted in limited numbers and in accordance with the policies linked above. If you want to include one or more external links in this article, please link directly to a webpage that provides detailed, encyclopedic information about the disease. Thanks, WhatamIdoing (talk) 02:33, 13 April 2008 (UTC)
[edit] Clinical trials
I removed a large section on various phase I, phase II and phase III trials without prejudice. Most Wikipedia articles, even on rare and incurable conditions, do not discuss ongoing research in such detail because it is entirely unclear which modalities will eventually reach clinical practice. Phase III trials are sort of the absolute maximum we cover. Rather than citing individual studies/agents/modalities, something could be said for discussing various trends in experimental science. JFW | T@lk 13:37, 14 April 2008 (UTC)
