GIMAP4

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GTPase, IMAP family member 4
Identifiers
Symbol(s) GIMAP4; FLJ11110; HIMAP4; IAN1; IMAP4; MSTP062; hIAN1
External IDs OMIM: 608087 MGI: 1349656 HomoloGene: 75084
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 55303 107526
Ensembl ENSG00000133574 ENSMUSG00000054435
Uniprot Q9NUV9 Q99JY3
Refseq NM_018326 (mRNA)
NP_060796 (protein)		 NM_174990 (mRNA)
NP_778155 (protein)
Location Chr 7: 149.9 - 149.9 Mb Chr 6: 48.61 - 48.62 Mb
Pubmed search [1] [2]

GTPase, IMAP family member 4, also known as GIMAP4, is a human gene.[1]

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1.[1]

[edit] References

  1. ^ a b Entrez Gene: GIMAP4 GTPase, IMAP family member 4.

[edit] Further reading

  • Dominguez O, Ashhab Y, Sabater L, et al. (1999). "Cloning of ARE-containing genes by AU-motif-directed display.". Genomics 54 (2): 278-86. doi:10.1006/geno.1998.5548. PMID 9828130. 
  • Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800. 
  • Stamm O, Krücken J, Schmitt-Wrede HP, et al. (2002). "Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36.". Gene 282 (1-2): 159-67. PMID 11814688. 
  • Cambot M, Aresta S, Kahn-Perlès B, et al. (2002). "Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells.". Blood 99 (9): 3293-301. PMID 11964296. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Krücken J, Schroetel RM, Müller IU, et al. (2005). "Comparative analysis of the human gimap gene cluster encoding a novel GTPase family.". Gene 341: 291-304. doi:10.1016/j.gene.2004.07.005. PMID 15474311. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Nitta T, Nasreen M, Seike T, et al. (2006). "IAN family critically regulates survival and development of T lymphocytes.". PLoS Biol. 4 (4): e103. doi:10.1371/journal.pbio.0040103. PMID 16509771. 
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