Geranoyl-CoA carboxylase

From Wikipedia, the free encyclopedia

In enzymology, a geranoyl-CoA carboxylase (EC 6.4.1.5) is an enzyme that catalyzes the chemical reaction

ATP + geranoyl-CoA + HCO₃- ADP + phosphate + 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA

The 3 substrates of this enzyme are ATP, geranoyl-CoA, and HCO3-, whereas its 3 products are ADP, phosphate, and 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is geranoyl-CoA:carbon-dioxide ligase (ADP-forming). Other names in common use include geranoyl coenzyme A carboxylase, and geranyl-CoA carboxylase. It employs one cofactor, biotin.

[edit] References

• IUBMB entry for 6.4.1.5
• BRENDA references for 6.4.1.5 (Recommended.)
• PubMed references for 6.4.1.5
• PubMed Central references for 6.4.1.5
• Google Scholar references for 6.4.1.5
• Seubert W, Fass E and Remberger U (1963). "Untersuchungen uber den bakteriellen Abbau von Isoprenoiden. III Reinigung und Eigenschaften der Geranylcarboxylase". Biochem. Z. 338: 265–275. 

[edit] External links

The CAS registry number for this enzyme class is 37324-35-9.

• IUBMB entry for 6.4.1.5

• KEGG entry for 6.4.1.5

• BRENDA entry for 6.4.1.5

• NiceZyme view of 6.4.1.5

• EC2PDB: PDB structures for 6.4.1.5

• PRIAM entry for 6.4.1.5

• PUMA2 entry for 6.4.1.5

• IntEnz: Integrated Enzyme entry for 6.4.1.5

• MetaCyc entry for 6.4.1.5

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047925: geranoyl-CoA carboxylase

• AMIGO entry for GO code 0047925: geranoyl-CoA carboxylase