Gene Tools

From Wikipedia, the free encyclopedia

Gene Tools, LLC is a limited liability company located in Philomath, Oregon, United States that manufactures Morpholino antisense oligos and delivery reagents[1][2]. Gene Tools was founded in 1997 and began regularly shipping custom-sequence Morpholino oligos in 2000. The manager and general partner, Dr. Jim Summerton, is a pioneer in antisense research[3], conceived of and was co-inventor of the Morpholino antisense oligo structural type[4] and founded the first antisense therapeutics company, AVI Bio Pharma Inc. (formerly AntiVirals Inc.).

[edit] Sources

  1. ^ Summerton, JE (2005). "Endo-porter: a novel reagent for safe, effective delivery of substances into cells." (Pubmed). Ann N Y Acad Sci 1058: 62–75. doi:10.1196/annals.1359.012. PMID 16394126. 
  2. ^ Morcos, PA (2001). "Achieving efficient delivery of morpholino oligos in cultured cells." (Pubmed). Genesis 30: 94–102. doi:10.1002/gene.1039. 
  3. ^ Summerton, JE (submitted 1973, published 1979). "Intracellular inactivation of specific nucleotide sequences: a general approach to the treatment of viral diseases and virally-mediated cancers.". Theoretical Biology 78: 77–99. doi:10.1016/0022-5193(79)90327-8. 
  4. ^ Summerton, J; Weller D (1997). "Morpholino Antisense Oligomers: Design, Preparation and Properties." (Pubmed). Antisense & Nucleic Acid Drug Development 7*: 187–95. 

[edit] External links