GBF1

From Wikipedia, the free encyclopedia

Golgi-specific brefeldin A resistance factor 1

Identifiers

GBF1; FLJ21263; FLJ21500; KIAA0248; MGC134877; MGC134878

External IDs

OMIM: 603698 MGI: 1861607 HomoloGene: 37897

Gene ontology
Molecular Function:	• ARF guanyl-nucleotide exchange factor activity • protein binding
Cellular Component:	• intracellular • Golgi apparatus
Biological Process:	• retrograde vesicle-mediated transport, Golgi to ER • regulation of ARF protein signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_004193 (mRNA)
NP_004184 (protein)

NM_178930 (mRNA)
NP_849261 (protein)

Location

Chr 10: 104 - 104.13 Mb

Chr 19: 46.21 - 46.34 Mb

Pubmed search

[1]

[2]

Golgi-specific brefeldin A resistance factor 1, also known as GBF1, is a human gene.^[1]

[edit] References

^ Entrez Gene: GBF1 golgi-specific brefeldin A resistance factor 1.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99-106. PMID 12168954.
Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.". DNA Res. 3 (5): 321-9, 341-54. PMID 9039502.
Mansour SJ, Herbrick JA, Scherer SW, Melançon P (1999). "Human GBF1 is a ubiquitously expressed gene of the sec7 domain family mapping to 10q24.". Genomics 54 (2): 323-7. doi:10.1006/geno.1998.5563. PMID 9828135.
Claude A, Zhao BP, Kuziemsky CE, et al. (1999). "GBF1: A novel Golgi-associated BFA-resistant guanine nucleotide exchange factor that displays specificity for ADP-ribosylation factor 5.". J. Cell Biol. 146 (1): 71-84. PMID 10402461.
Kawamoto K, Yoshida Y, Tamaki H, et al. (2003). "GBF1, a guanine nucleotide exchange factor for ADP-ribosylation factors, is localized to the cis-Golgi and involved in membrane association of the COPI coat.". Traffic 3 (7): 483-95. PMID 12047556.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
García-Mata R, Sztul E (2003). "The membrane-tethering protein p115 interacts with GBF1, an ARF guanine-nucleotide-exchange factor.". EMBO Rep. 4 (3): 320-5. doi:10.1038/sj.embor.embor762. PMID 12634853.
Claude A, Zhao BP, Melançon P (2003). "Characterization of alternatively spliced and truncated forms of the Arf guanine nucleotide exchange factor GBF1 defines regions important for activity.". Biochem. Biophys. Res. Commun. 303 (1): 160-9. PMID 12646181.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10.". Nature 429 (6990): 375-81. doi:10.1038/nature02462. PMID 15164054.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain.". Mol. Cell Proteomics 3 (11): 1093-101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Niu TK, Pfeifer AC, Lippincott-Schwartz J, Jackson CL (2005). "Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi.". Mol. Biol. Cell 16 (3): 1213-22. doi:10.1091/mbc.E04-07-0599. PMID 15616190.
Szul T, Garcia-Mata R, Brandon E, et al. (2005). "Dissection of membrane dynamics of the ARF-guanine nucleotide exchange factor GBF1.". Traffic 6 (5): 374-85. doi:10.1111/j.1600-0854.2005.00282.x. PMID 15813748.
Roy SK, Hu J, Meng Q, et al. (2006). "Development of monoclonal antibodies against GBF1 and their use in studying its functions.". J. Interferon Cytokine Res. 25 (11): 666-73. doi:10.1089/jir.2005.25.666. PMID 16318580.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.
Zhao X, Claude A, Chun J, et al. (2006). "GBF1, a cis-Golgi and VTCs-localized ARF-GEF, is implicated in ER-to-Golgi protein traffic.". J. Cell. Sci. 119 (Pt 18): 3743-53. doi:10.1242/jcs.03173. PMID 16926190.
Belov GA, Altan-Bonnet N, Kovtunovych G, et al. (2007). "Hijacking components of the cellular secretory pathway for replication of poliovirus RNA.". J. Virol. 81 (2): 558-67. doi:10.1128/JVI.01820-06. PMID 17079330.