GB virus C

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GB Virus C (GBV-C) is a species of virus in the Flaviviridae family which has not yet been assigned to a genus. GBV-C has high homology to the Hepatitis G virus. There have been reports that HIV patients coinfected with GBV-C can survive longer with the HI Virus. Research on how the immune system is affected in patients coinfected with this virus is going on.[1] [2]

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[edit] References

  1. ^ Mosam A, Sathar MA, Dawood H, Cassol E, Esterhuizen TM, Coovadia HM (2007). "Effect of GB virus C co-infection on response to generic HAART in African patients with HIV-1 clade C infection" 21 (10): 1377–1379. doi:10.1097/QAD.0b013e3281532cb8. PMID 17545721. 
  2. ^ Jung S, Eichenmüller M, Donhauser N, et al (2007). "HIV entry inhibition by the envelope 2 glycoprotein of GB virus C". AIDS 21 (5): 645–7. doi:10.1097/QAD.0b013e32803277c7. PMID 17314528. 

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[edit] Further reading

  • Leary TP, Muerhoff AS, Simons JN, Pilot-Matias TJ, Erker JC, Chalmers ML, Schlauder GG, Dawson GJ, Desai SM, Mushahwar IK (1996). "Sequence and genomic organization of GBV-C: a novel member of the flaviviridae associated with human non-A-E hepatitis". J. Med. Virol. 48 (1): 60–7. doi:10.1002/(SICI)1096-9071(199601)48:1<60::AID-JMV10>3.0.CO;2-A. PMID 8825712. 
  • Simons JN, Desai SM, Schultz DE, Lemon SM, Mushahwar IK (1996). "Translation initiation in GB viruses A and C: evidence for internal ribosome entry and implications for genome organization". J. Virol. 70 (9): 6126–35. PMID 8709237. 
  • Birkenmeyer LG, Desai SM, Muerhoff AS, Leary TP, Simons JN, Montes CC, Mushahwar IK (1998). "Isolation of a GB virus-related genome from a chimpanzee". J. Med. Virol. 56 (1): 44–51. PMID 9700632. 

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