GAS2L1

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Growth arrest-specific 2 like 1
Identifiers
Symbol(s) GAS2L1; GAR22; MGC17243
External IDs OMIM: 602128 MGI: 1926176 HomoloGene: 4733
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 10634 78926
Ensembl ENSG00000185340 ENSMUSG00000034201
Uniprot Q99501 Q8JZP9
Refseq NM_006478 (mRNA)
NP_006469 (protein)		 NM_030228 (mRNA)
NP_084504 (protein)
Location Chr 22: 28.03 - 28.04 Mb Chr 11: 4.96 - 4.97 Mb
Pubmed search [1] [2]

Growth arrest-specific 2 like 1, also known as GAS2L1, is a human gene.[1]

The protein encoded by this gene, a member of the GAS2 family, is similar in sequence to the mouse protein Gas2, an actin-associated protein expressed at high levels in growth-arrested cells. Expression of the mouse Gas2 gene is negatively regulated by serum and growth factors. Three transcript variants encoding two different isoforms have been found for this gene.[1]

[edit] References

  1. ^ a b Entrez Gene: GAS2L1 growth arrest-specific 2 like 1.

[edit] Further reading

  • Brancolini C, Bottega S, Schneider C (1992). "Gas2, a growth arrest-specific protein, is a component of the microfilament network system.". J. Cell Biol. 117 (6): 1251-61. PMID 1607387. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Zucman-Rossi J, Legoix P, Thomas G (1997). "Identification of new members of the Gas2 and Ras families in the 22q12 chromosome region.". Genomics 38 (3): 247-54. doi:10.1006/geno.1996.0625. PMID 8975699. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Weinmann AS, Yan PS, Oberley MJ, et al. (2002). "Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis.". Genes Dev. 16 (2): 235-44. doi:10.1101/gad.943102. PMID 11799066. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Goriounov D, Leung CL, Liem RK (2003). "Protein products of human Gas2-related genes on chromosomes 17 and 22 (hGAR17 and hGAR22) associate with both microfilaments and microtubules.". J. Cell. Sci. 116 (Pt 6): 1045-58. PMID 12584248. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
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