Galactose oxidase

From Wikipedia, the free encyclopedia

In enzymology, a galactose oxidase (EC 1.1.3.9) is an enzyme that catalyzes the chemical reaction

D-galactose + O₂ D-galacto-hexodialdose + H₂O₂

Thus, the two substrates of this enzyme are D-galactose and O₂, whereas its two products are D-galacto-hexodialdose and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is D-galactose:oxygen 6-oxidoreductase. Other names in common use include D-galactose oxidase, and beta-galactose oxidase. This enzyme participates in galactose metabolism. It employs one cofactor, copper.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes 1GOF, 1GOG, 1GOH, 1K3I, 1T2X, 2EIB, 2EIC, 2EID, and 2EIE.

[edit] References

• IUBMB entry for 1.1.3.9
• BRENDA references for 1.1.3.9 (Recommended.)
• PubMed references for 1.1.3.9
• PubMed Central references for 1.1.3.9
• Google Scholar references for 1.1.3.9
• AVIGAD G, AMARAL D, ASENSIO C, HORECKER BL (1962). "The D-galactose oxidase of Polyporus circinatus". J. Biol. Chem. 237: 2736–43. PMID 13863403. 

[edit] External links

The CAS registry number for this enzyme class is 9028-79-9.

• IUBMB entry for 1.1.3.9

• KEGG entry for 1.1.3.9

• BRENDA entry for 1.1.3.9

• NiceZyme view of 1.1.3.9

• EC2PDB: PDB structures for 1.1.3.9

• PRIAM entry for 1.1.3.9

• PUMA2 entry for 1.1.3.9

• IntEnz: Integrated Enzyme entry for 1.1.3.9

• MetaCyc entry for 1.1.3.9

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0045480: galactose oxidase

• AMIGO entry for GO code 0045480: galactose oxidase