Galactose-6-phosphate isomerase

From Wikipedia, the free encyclopedia

In enzymology, a galactose-6-phosphate isomerase (EC 5.3.1.26) is an enzyme that catalyzes the chemical reaction

D-galactose 6-phosphate D-tagatose 6-phosphate

Hence, this enzyme has one substrate, D-galactose 6-phosphate, and one product, D-tagatose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-galactose-6-phosphate aldose-ketose-isomerase. This enzyme participates in galactose metabolism.

[edit] References

• IUBMB entry for 5.3.1.26
• BRENDA references for 5.3.1.26 (Recommended.)
• PubMed references for 5.3.1.26
• PubMed Central references for 5.3.1.26
• Google Scholar references for 5.3.1.26
• de Vos WM, Boerrigter I, van Rooyen RJ, Reiche B, Hengstenberg W (1990). "Characterization of the lactose-specific enzymes of the phosphotransferase system in Lactococcus lactis". J. Biol. Chem. 265: 22554–60. PMID 2125052. 
• van Rooijen RJ, van Schalkwijk S, de Vos WM (1991). "Molecular cloning, characterization, and nucleotide sequence of the tagatose 6-phosphate pathway gene cluster of the lactose operon of Lactococcus lactis". J. Biol. Chem. 266: 7176–81. PMID 1901863. 

[edit] External links

The CAS registry number for this enzyme class is 39433-98-2.

• IUBMB entry for 5.3.1.26

• KEGG entry for 5.3.1.26

• BRENDA entry for 5.3.1.26

• NiceZyme view of 5.3.1.26

• EC2PDB: PDB structures for 5.3.1.26

• PRIAM entry for 5.3.1.26

• PUMA2 entry for 5.3.1.26

• IntEnz: Integrated Enzyme entry for 5.3.1.26

• MetaCyc entry for 5.3.1.26

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050044: galactose-6-phosphate isomerase

• AMIGO entry for GO code 0050044: galactose-6-phosphate isomerase