Galactonate dehydratase

From Wikipedia, the free encyclopedia

In enzymology, a galactonate dehydratase (EC 4.2.1.6) is an enzyme that catalyzes the chemical reaction

D-galactonate 2-dehydro-3-deoxy-D-galactonate + H₂O

Hence, this enzyme has one substrate, D-galactonate, and two products, 2-dehydro-3-deoxy-D-galactonate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming). Other names in common use include D-galactonate dehydrase, D-galactonate dehydratase, and D-galactonate hydro-lyase. This enzyme participates in galactose metabolism.

[edit] References

• IUBMB entry for 4.2.1.6
• BRENDA references for 4.2.1.6 (Recommended.)
• PubMed references for 4.2.1.6
• PubMed Central references for 4.2.1.6
• Google Scholar references for 4.2.1.6
• DE LEY J, DOUDOROFF M (1957). "The metabolism of D-galactose in Pseudomonas saccharophila". J. Biol. Chem. 227: 745–57. PMID 13462997. 

[edit] External links

The CAS registry number for this enzyme class is 9024-38-8.

• IUBMB entry for 4.2.1.6

• KEGG entry for 4.2.1.6

• BRENDA entry for 4.2.1.6

• NiceZyme view of 4.2.1.6

• EC2PDB: PDB structures for 4.2.1.6

• PRIAM entry for 4.2.1.6

• PUMA2 entry for 4.2.1.6

• IntEnz: Integrated Enzyme entry for 4.2.1.6

• MetaCyc entry for 4.2.1.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008869: galactonate dehydratase

• AMIGO entry for GO code 0008869: galactonate dehydratase