Galactitol 2-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a galactitol 2-dehydrogenase (EC 1.1.1.16) is an enzyme that catalyzes the chemical reaction

galactitol + NAD⁺ D-tagatose + NADH + H⁺

Thus, the two substrates of this enzyme are galactitol and NAD⁺, whereas its 3 products are D-tagatose, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol:NAD+ 2-oxidoreductase. This enzyme is also called dulcitol dehydrogenase. This enzyme participates in galactose metabolism.

[edit] References

• IUBMB entry for 1.1.1.16
• BRENDA references for 1.1.1.16 (Recommended.)
• PubMed references for 1.1.1.16
• PubMed Central references for 1.1.1.16
• Google Scholar references for 1.1.1.16
• Shaw DRD (1956). "Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase". Biochem. J. 64: 394–405. 

[edit] External links

The CAS registry number for this enzyme class is 9028-23-3.

• IUBMB entry for 1.1.1.16

• KEGG entry for 1.1.1.16

• BRENDA entry for 1.1.1.16

• NiceZyme view of 1.1.1.16

• EC2PDB: PDB structures for 1.1.1.16

• PRIAM entry for 1.1.1.16

• PUMA2 entry for 1.1.1.16

• IntEnz: Integrated Enzyme entry for 1.1.1.16

• MetaCyc entry for 1.1.1.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047713: galactitol 2-dehydrogenase

• AMIGO entry for GO code 0047713: galactitol 2-dehydrogenase