Galactitol-1-phosphate 5-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a galactitol-1-phosphate 5-dehydrogenase (EC 1.1.1.251) is an enzyme that catalyzes the chemical reaction

galactitol-1-phosphate + NAD⁺ L-tagatose 6-phosphate + NADH + H⁺

Thus, the two substrates of this enzyme are galactitol-1-phosphate and NAD⁺, whereas its 3 products are L-tagatose 6-phosphate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol-1-phosphate:NAD+ oxidoreductase. This enzyme participates in galactose metabolism. It employs one cofactor, zinc.

[edit] References

• IUBMB entry for 1.1.1.251
• BRENDA references for 1.1.1.251 (Recommended.)
• PubMed references for 1.1.1.251
• PubMed Central references for 1.1.1.251
• Google Scholar references for 1.1.1.251
• Nobelmann B, Lengeler JW (1995). "Sequence of the gat operon for galactitol utilization from a wild-type strain EC3132 of Escherichia coli". Biochim. Biophys. Acta. 1262: 69–72. PMID 7772602. 

[edit] External links

The CAS registry number for this enzyme class is 167618-25-9.

• IUBMB entry for 1.1.1.251

• KEGG entry for 1.1.1.251

• BRENDA entry for 1.1.1.251

• NiceZyme view of 1.1.1.251

• EC2PDB: PDB structures for 1.1.1.251

• PRIAM entry for 1.1.1.251

• PUMA2 entry for 1.1.1.251

• IntEnz: Integrated Enzyme entry for 1.1.1.251

• MetaCyc entry for 1.1.1.251

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008868: galactitol-1-phosphate 5-dehydrogenase

• AMIGO entry for GO code 0008868: galactitol-1-phosphate 5-dehydrogenase