Galactarate dehydratase

From Wikipedia, the free encyclopedia

In enzymology, a galactarate dehydratase (EC 4.2.1.42) is an enzyme that catalyzes the chemical reaction

D-galactarate 5-dehydro-4-deoxy-D-glucarate + H₂O

Hence, this enzyme has one substrate, D-galactarate, and two products, 5-dehydro-4-deoxy-D-glucarate and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is D-galactarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming). This enzyme is also called D-galactarate hydro-lyase. This enzyme participates in ascorbate and aldarate metabolism.

[edit] References

• IUBMB entry for 4.2.1.42
• BRENDA references for 4.2.1.42 (Recommended.)
• PubMed references for 4.2.1.42
• PubMed Central references for 4.2.1.42
• Google Scholar references for 4.2.1.42
• Blumenthal HJ and Jepson T (1966). "Galactarate dehydrase". Methods Enzymol. 9: 665–669. 

[edit] External links

The CAS registry number for this enzyme class is 37290-78-1.

• IUBMB entry for 4.2.1.42

• KEGG entry for 4.2.1.42

• BRENDA entry for 4.2.1.42

• NiceZyme view of 4.2.1.42

• EC2PDB: PDB structures for 4.2.1.42

• PRIAM entry for 4.2.1.42

• PUMA2 entry for 4.2.1.42

• IntEnz: Integrated Enzyme entry for 4.2.1.42

• MetaCyc entry for 4.2.1.42

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008867: galactarate dehydratase

• AMIGO entry for GO code 0008867: galactarate dehydratase