Talk:G protein

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I tried to clean up this article a bit, but I really couldn't figure out what the original author was saying in the last paragraph. I'm also not sure what Greek letter he/she meant to put in with that last little rectangle. If I get a chance in the next few days, I'll try to re-write that last paragraph, but anyone reading this should feel free to do it themselves if they feel up to it. I'm also not sure what we should do about the small G protiens. Is the link to small GTPase enough? Also, check out GTPase and see if there's too much overlap.

Contents 1 To Sayeth 2 Possible Copyvio 3 incomplete article 4 Diagrams

[edit] To Sayeth

Just wanna say that you've done a great job re-editing this page already.
I can't figure out that rectangle, either. I guess this means I should hit the books ..... :-)
-- PFHLai 22:36, 2004 May 25 (UTC)

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I don't understand why Jiang would label this G protein page "clean enough". The last paragraph is not fixed yet, and there is still too little info on the beta and gamma subunits ....  ?????? -- PFHLai 00:25, 2004 May 26 (UTC)

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For the record, Sayeth has fixed this page, and it's indeed "clean enough" now. Maybe Jiang is psychic or sth .....  :-)
-- PFHLai 15:34, 2004 Jun 6 (UTC)

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Of course Jiang is psychic, he's a super-wikipedian! -- Sayeth 16:38, 8 Jun 2004 (UTC)

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GDP stands for Guanosine_diphosphate. Is this guanine diphosphate then equally correct? I assume not, therefore I changed it. WouterVH 15:08, 6 May 2005 (UTC)

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The part about "When a ligand activates the G-protein coupled receptor, the G-protein binds to the receptor, releases its bound GDP from the Gα subunit, and binds a new molecule of GTP." is a little conusing under Receptor-activated G-proteins. Could someone clear it up?--Dan 02:10, 21 January 2006 (UTC)

[edit] Possible Copyvio

These two edits [1] [2] may be a copyright violations. The editor will only divulge that the source is "online" and has made numerous similar edits that are copyright violations. I propose removing all of what remains from those edits: the Introduction, Serpentine Receptors, and G protein–coupled receptors Sections. --Ronz 16:45, 19 October 2006 (UTC)

• I think you should give it a week and if the sources aren't found, then remove them. These sections can be easily re-written and sourced; G-proteins are well known to most molecular/cell biologists, so I don't think it will be hard to find contributors to this page. --MPW 21:34, 20 October 2006 (UTC)

Agreed. If I could find the source and knew it was a copyvio, I would be more inclined to get rid of it quicker. --Ronz 00:46, 21 October 2006 (UTC)

I removed the information in question November 20. --Ronz 02:47, 9 December 2006 (UTC)

[edit] incomplete article

Need to include info on G_s, G_i.

• beta-adrenergic receptors are Gs: cAMP up (A-cyclase stimulated), stimulation of metabolism, stimulation of heart rate

smooth muscle relaxation in certain blood vessels

• alpha2-adrenergic receptors are Gi: cAMP down (A-cyclase inhibited)
• alpha1-adrenergic receptors are G: hydrolyze PIP2 to IP3 and DAG

alpha adrenergic receptors functions: smooth muscle contraction in other blood vessels 129.31.72.52 10:08, 12 June 2007 (UTC)

[edit] Diagrams

Although anyone interested in G-proteins wouldn't have a clue what diphospho and triphospho guanine look like, and how to tell them apart.

You've gone image mad, and it doesn't help comprehension

Since, the link for G protein 12/13 alpha sub unit wasn't linking to the intended page, I've corrrected the anomaly. -KC Panchal. —Preceding unsigned comment added by 59.184.188.248 (talk) 12:53, 17 March 2008 (UTC)