Talk:G-quadruplex
From Wikipedia, the free encyclopedia
[edit] sequence
d(GGTTAG) - is there a reason for this form of noting the sequence? a) as a sidenote d(sequence) probably means that it is the deoxy form of the sequence - will this be understood by the casual reader? b) why GGTTAG and not e.g. TTAGGG - it will be the Gs that form the quadruplex, so if the sequence repeats anyways, why split up the Gs? Iridos 01:40, 11 May 2007 (UTC)
a) It's the standard nomenclature, and I don't see how it could be massively improved b) There is - the enzyme telomerase, which elongates telomeres, contains an inbuilt RNA template, that adds the repeat d(GGTTAG) many times. Hence there is a starting point for the sequence. Jlh29 16:15, 7 June 2007 (UTC)
[edit] repeat edits/reversion
Could 202.46.222.112 and 121.247.190.198 please cease reinserting papers - wikipedia is not pubmed, and does not need multiple listings of all papers published by their group! If they would like to suggest a change, can they discuss it here first.