Talk:G-quadruplex

From Wikipedia, the free encyclopedia

WikiProject Genetics This article is part of WikiProject Genetics, an attempt to build a comprehensive and detailed guide to genetics on Wikipedia. If you would like to participate, you can edit this page, or visit the project page to join the project and/or contribute to the discussion.
??? This article has not yet received a rating on the quality scale.
??? This article has not yet received an importance rating.
Molecular and Cellular Biology WikiProject This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The WikiProject's current monthly collaboration is focused on improving Restriction enzyme.
Start This article has been rated as start-Class on the assessment scale.
Low This article is on a subject of low-importance within molecular and cellular biology.

Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need.

[edit] sequence

d(GGTTAG) - is there a reason for this form of noting the sequence? a) as a sidenote d(sequence) probably means that it is the deoxy form of the sequence - will this be understood by the casual reader? b) why GGTTAG and not e.g. TTAGGG - it will be the Gs that form the quadruplex, so if the sequence repeats anyways, why split up the Gs? Iridos 01:40, 11 May 2007 (UTC)

a) It's the standard nomenclature, and I don't see how it could be massively improved b) There is - the enzyme telomerase, which elongates telomeres, contains an inbuilt RNA template, that adds the repeat d(GGTTAG) many times. Hence there is a starting point for the sequence. Jlh29 16:15, 7 June 2007 (UTC)

[edit] repeat edits/reversion

Could 202.46.222.112 and 121.247.190.198 please cease reinserting papers - wikipedia is not pubmed, and does not need multiple listings of all papers published by their group! If they would like to suggest a change, can they discuss it here first.